Pneumococcal purpura fulminans in a 25-year-old patient with liver cirrhosis due to autoimmune hepatitis. 

 -  2022 
<br/><br/> Purpura fulminans (PF) is a skin disorder with high morbidity and mortality which is characterized by microvascular thrombosis and development of hemorrhagic necrosis. PF can be caused by acute infection, most commonly due to Neisseria meningitidis, followed by Streptococcus pneumoniae. Prior reports describe cases of pneumococcal PF occurring in patients with asplenia or hyposplenia, though cases have also been reported in otherwise healthy adults without known splenic disease. Herein, we report a young adult patient with cirrhosis due to autoimmune hepatitis who had not received pneumococcal vaccination and developed rapidly progressive fatal S. pneumoniae sepsis with PF. Copyright © 2022 The Authors. Published by Elsevier Ltd. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>2214-2509 
<br/><br/><label>Standard No.: </label>10.1016/j.idcr.2022.e01610 [doi] PMC9429787 [pmc] S2214-2509(22)00238-4 [pii] 
<br/><br/><label>Subjects--Topical Terms: </label><br/>IN PROCESS -- NOT YET INDEXED
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Washington Hospital Center
<br/><br/><label>Index Terms--Occupation: </label><br/>Infectious Disease Fellowship<br/>Medicine/Internal Medicine
<br/><br/><label>Index Terms--Function: </label><br/>Case Reports