TY  - BOOK
AU  - Ruiz Gaviria, Rafael
AU  - Williamson, Sarah J
TI  - Pneumococcal purpura fulminans in a 25-year-old patient with liver cirrhosis due to autoimmune hepatitis
SN  - 2214-2509
PY  - 2022///
KW  - IN PROCESS -- NOT YET INDEXED
KW  - MedStar Washington Hospital Center
KW  - Infectious Disease Fellowship
KW  - Medicine/Internal Medicine
KW  - Case Reports
N2  - Purpura fulminans (PF) is a skin disorder with high morbidity and mortality which is characterized by microvascular thrombosis and development of hemorrhagic necrosis. PF can be caused by acute infection, most commonly due to Neisseria meningitidis, followed by Streptococcus pneumoniae. Prior reports describe cases of pneumococcal PF occurring in patients with asplenia or hyposplenia, though cases have also been reported in otherwise healthy adults without known splenic disease. Herein, we report a young adult patient with cirrhosis due to autoimmune hepatitis who had not received pneumococcal vaccination and developed rapidly progressive fatal S. pneumoniae sepsis with PF. Copyright © 2022 The Authors. Published by Elsevier Ltd
UR  - https://dx.doi.org/10.1016/j.idcr.2022.e01610
ER  -