TY - BOOK AU - Garcia-Garcia, Hector M TI - The influence of coronary plaque morphology assessed by optical coherence tomography on final microvascular function after stenting in patients with ST-elevation myocardial infarction SN - 0954-6928 PY - 2017/// KW - *Angioplasty, Balloon, Coronary/is [Instrumentation] KW - *Coronary Circulation KW - *Coronary Vessels/dg [Diagnostic Imaging] KW - *Microcirculation KW - *Plaque, Atherosclerotic KW - *ST Elevation Myocardial Infarction/th [Therapy] KW - *Stents KW - *Tomography, Optical Coherence KW - Aged KW - Angioplasty, Balloon, Coronary/ae [Adverse Effects] KW - Cardiac Catheterization KW - Coronary Angiography KW - Coronary Vessels/pa [Pathology] KW - Coronary Vessels/pp [Physiopathology] KW - Electrocardiography KW - Female KW - Humans KW - Male KW - Middle Aged KW - Predictive Value of Tests KW - Prospective Studies KW - ST Elevation Myocardial Infarction/dg [Diagnostic Imaging] KW - ST Elevation Myocardial Infarction/pa [Pathology] KW - ST Elevation Myocardial Infarction/pp [Physiopathology] KW - Time Factors KW - Treatment Outcome KW - Vascular Resistance KW - MedStar Heart & Vascular Institute KW - Journal Article N1 - Available online from MWHC library: February 2000 - present N2 - CONCLUSION: IMR measured before stenting is independent of the appearances of the culprit coronary plaque within the infarct-related artery. IMR after stenting, and more importantly, the change in IMR after stenting, reflect the degree of distal embolization during stent implantation; OBJECTIVES: The index of microcirculatory resistance (IMR) provides a reproducible assessment of the status of coronary microvasculature in patients with ST-elevation myocardial infarction (STEMI). Frequency-domain optical coherence tomography (FD-OCT) enables detailed assessment of the morphology of coronary plaque.We sought to determine the influence of the initial culprit coronary plaque anatomy within the infarct-related artery on IMR after stenting in STEMI; PATIENTS AND METHODS: In 25 STEMI patients IMR was measured immediately before and after stent implantation. FD-OCT imaging was performed at the same time points and atherothrombotic volume (ATV) before stenting, prolapsed+floating ATV after stenting and DELTAATV was measured using three different strategies; RESULTS: There were no relationships between preprocedural IMR and FD-OCT parameters. Prestenting IMR was related only to pain to wire time (P: 0.02). Irrespective of the method adopted, the final IMR was related to prestenting ATV (p: 0.44, P: 0.03 for method I, p: 0.48, P: 0.02 for method II and p: 0.30, P: 0.06 for method III) and DELTAATV (p: 0.41, P: 0.04 for method II and p: 0.44, P: 0.03 for method III) UR - https://dx.doi.org/10.1097/MCA.0000000000000458 ER -