TY  - BOOK
AU  - Howard, Barbara V
TI  - Sedentary time and postmenopausal breast cancer incidence
SN  - 0957-5243
PY  - 2017///
KW  - *Breast Neoplasms/ep [Epidemiology]
KW  - *Postmenopause
KW  - *Sedentary Lifestyle
KW  - Aged
KW  - Breast Neoplasms/eh [Ethnology]
KW  - Continental Population Groups
KW  - Ethnic Groups
KW  - Exercise
KW  - Female
KW  - Humans
KW  - Incidence
KW  - Middle Aged
KW  - Proportional Hazards Models
KW  - Prospective Studies
KW  - Surveys and Questionnaires
KW  - MedStar Health Research Institute
KW  - Journal Article
N2  - CONCLUSIONS: Results from this study do not support an association between sedentary time and breast cancer incidence; METHODS: The Women's Health Initiative Observational Study is a prospective cohort among women ages 50-79 years at baseline (1994-1998) (analytic cohort=70,233). Baseline questionnaire data were used to estimate time spent sitting and total sedentary time. Associations between time spent sitting and invasive breast cancer incidence overall (n=4,115 cases through September 2015), and by hormone receptor subtypes, were investigated using Cox proportional hazards regression. Analyses were replicated stratified by race/ethnicity, body measurements, and physical activity; PURPOSE: The objective of this study was to evaluate the prospective association between sedentary time and postmenopausal breast cancer incidence, and whether associations differ by race/ethnicity, physical activity levels, and body measurements; RESULTS: Among women in this study, 34.5% reported<=5 h/day sitting, 40.9% reported 6-9 h/day and 24.7% reported>=10 h/day. Time spent sitting (>=10 vs. <=5 h/day adjusted HR=1.00, 95% CI 0.92-1.09) was not associated with breast cancer incidence, regardless of hormone receptor subtype. Associations did not differ by race/ethnicity, physical activity, or body measurements
UR  - https://dx.doi.org/10.1007/s10552-017-0968-x
ER  -