Hepatitis B-associated hepatocellular carcinoma in a young Haitian man: a review of screening guidelines. - 2019

Hepatocellular carcinoma (HCC) is a terminal, yet preventable, outcome of untreated infection with hepatitis B virus (HBV). HBV is endemic in many areas of Latin America and the Caribbean, including Haiti. Haitians have the highest incidence of liver cancer among Caribbean immigrants. Unfortunately, many of these patients are not screened, despite current guidelines. As HBV is treatable, screening of high-risk populations is crucial to early intervention and prevention of poor outcomes. We highlight the case of a young Haitian male immigrant who presented with unintentional weight loss and epigastric pain and found to have HCC associated with HBV. Despite chemotherapy, the patient died 15 months after diagnosis. Increased awareness of HBV among patients from high-incidence countries may result in early recognition of this disease and reduced morbidity and mortality from devastating complications. Copyright (c) BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.


English

1757-790X

10.1136/bcr-2019-230530 [doi] 12/10/e230530 [pii]


*Carcinoma, Hepatocellular/vi [Virology]
*Hepatitis B, Chronic/co [Complications]
*Liver Neoplasms/vi [Virology]
Adult
Antineoplastic Agents/tu [Therapeutic Use]
Carcinoma, Hepatocellular/dg [Diagnostic Imaging]
Carcinoma, Hepatocellular/dt [Drug Therapy]
Deoxycytidine/aa [Analogs & Derivatives]
Deoxycytidine/tu [Therapeutic Use]
Diagnosis, Differential
Fatal Outcome
Haiti
Hepatitis B, Chronic/di [Diagnosis]
Humans
Liver Neoplasms/dg [Diagnostic Imaging]
Liver Neoplasms/dt [Drug Therapy]
Male
Mass Screening
Oxaliplatin/tu [Therapeutic Use]
Practice Guidelines as Topic
Sorafenib/tu [Therapeutic Use]
Tomography, X-Ray Computed


MedStar Washington Hospital Center


Medicine/Internal Medicine


Journal Article