TY - BOOK AU - Giladi, Aviram M TI - Coronary Artery Disease Association With Arterial Calcifications on Routine Hand Radiographs SN - 0363-5023 PY - 2019/// KW - *Coronary Artery Disease/di [Diagnosis] KW - *Hand/bs [Blood Supply] KW - *Hand/dg [Diagnostic Imaging] KW - *Vascular Calcification/dg [Diagnostic Imaging] KW - Adult KW - Aged KW - Aged, 80 and over KW - Coronary Angiography KW - Exercise Test KW - Female KW - Humans KW - Male KW - Middle Aged KW - Retrospective Studies KW - Risk Factors KW - Curtis National Hand Center KW - Journal Article N1 - Available in print through MWHC library: 1999 - 2002, Available online from MWHC library: 1995 - present N2 - CONCLUSIONS: The current data demonstrate that arterial calcifications on hand radiographs are independently associated with CAD. This may represent an opportunity to the treating physician as a point of referral or investigation for underlying or occult CAD; METHODS: A record review from a single institution identified 345 patients with both hand radiographs and CAD screening with cardiac stress testing or coronary angiography. Patients with chronic kidney disease, end-stage renal disease, or incomplete hand films were excluded. We reviewed x-rays for findings of arterial calcifications. Cardiac testing results were used to establish a baseline diagnosis of CAD. We made group comparisons and employed multivariable logistic regression to evaluate the association between upper-extremity calcification and CAD; PURPOSE: Arterial calcifications in the lower extremity, chest, and cardiac vessels have been linked to coronary artery disease (CAD). However, the relation between arterial calcifications observed on routine hand and upper-extremity radiographs and atherosclerosis has not been determined. This study examined whether arterial calcifications found on hand radiographs are associated with CAD; RESULTS: A total of 210 patients met inclusion criteria: 155 with CAD and 55 without it. Mean age was 72 years, body mass index was 28.8, and 54% were male. Patients had comorbidities of hypertension (91%), hyperlipidemia (87%), diabetes (39%), cerebrovascular accident (9%), and a history of tobacco use (53%). Of 155 CAD patients, 67 had arterial calcifications on hand radiographs (43%), compared with 6 of 55 without it (11%). In a multivariable model controlling for sex, hyperlipidemia, and diabetes, the presence of arterial calcifications on hand plain films indicated a 6.2-fold increased odds of CAD; TYPE OF STUDY/LEVEL OF EVIDENCE: Prevalence III. Copyright (c) 2019 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved UR - https://dx.doi.org/10.1016/j.jhsa.2019.10.004 UR - https://dx.doi.org/10.1016/j.jhsa.2019.10.004 ER -