Independence of Urinary Symptoms and Urinary Dipstick Results in Voiders With Neurogenic Bladder. 

 -  2022 
<br/><br/>Available in print through MWHC library: 1999 - Winter 2007 
<br/><br/> Background: Urinary symptoms and urinary tract infection (UTI) are frequent and burdensome problems associated with neurogenic lower urinary tract dysfunction.  Conclusion: Among people with SCI or MS who void, self-administered urine dipstick results and urinary symptom reporting contribute independent information for clinical decision making. Copyright © 2022 American Spinal Injury Association.  Methods: Prospective 12-month cohort study of 76 participants with SCI or MS who manage their bladders by voiding. Eligibility criteria included adults >=18 years old, at least three UTIs since diagnosis, and residence in the United States. Participants completed the Urinary Symptoms Questionnaire for Neurogenic Bladder-Voider version (USQNB-V) biweekly (26 assessments) and tested their urine by dipstick at the same time. Symptom burden was estimated based on endorsements of USQNB-V symptoms classified as clinically actionable (9), bladder function (8), and urine quality (4). Urine dipstick results assessed were leukocyte esterase (LE) and nitrite (NIT).  Objectives: To determine whether an association exists between urinary symptoms and urine dipstick results among individuals with spinal cord injury (SCI) or multiple sclerosis (MS).  Results: Participants were stratified into four groups based on etiology of neurologic dysfunction and whether they ever experienced any urinary symptoms (USx): SCI+USx (n = 14), SCI+NoUSx (n = 5), MS+USx (n = 32), and MS+NoUSx (n = 25). In descending order, symptom burden was greatest for the MS+USx group, followed by both SCI groups; it was lowest for MS+NoUSx. We assessed multiple definitions of "positive" dipstick and found evidence of independence of USQNB-V symptoms and urinary dipstick results with each definition. In each group, the median (and majority) of strong positive dipsticks did not coincide with any symptoms. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>1082-0744 
<br/><br/><label>Standard No.: </label>10.46292/sci21-00006 [doi] PMC9009195 [pmc] 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Spinal Cord Injuries<br/>*Urinary Bladder, Neurogenic<br/>*Urinary Tract Infections<br/>Adolescent<br/>Adult<br/>Cohort Studies<br/>Female<br/>Humans<br/>Male<br/>Prospective Studies<br/>Spinal Cord Injuries/co [Complications]<br/>Urinary Bladder, Neurogenic/et [Etiology]<br/>Urinary Tract Infections/di [Diagnosis]
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Health Research Institute<br/>MedStar National Rehabilitation Network
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article