Intravascular Lithotripsy Facilitated Percutaneous Endovascular Intervention of the Aortic Arch: A Single-Center Experience. - 2020

Available in print through MWHC library: 2002 - present

BACKGROUND: Intravascular lithotripsy (IVL) (Shockwave Medical, Inc., Fremont, California, USA) is a novel technology used to modify heavily calcified atherosclerotic plaque in vessels to help facilitate percutaneous coronary intervention and has been shown to be effective in treating critical lesions within the lower limbs. In addition, studies are currently underway evaluating IVL's feasibility in de novo calcified stenotic coronary arteries before stenting. The use and associated complications of IVL in other vascular territories are underreported. We report our institution's initial experience using IVL for the treatment of complex, heavily calcified lesions within the aortic arch vessels. CONCLUSION: IVL offers promising technology to facilitate the treatment of complex lesions in the vessels of the aortic arch. We do not promote the use of IVL but promote prospective clinical trials to assess the safety and efficacy of this technology in this vascular territory. Copyright (c) 2020 Elsevier Inc. All rights reserved. METHODS AND RESULTS: We treated five patients with IVL of the aortic arch vessels, including the carotid (2), subclavian (2), and innominate arteries. Four of the five patients underwent successful IVL treatment and intervention without complications. One patient (carotid intervention) developed acute right eye blindness post-procedure, thought to be due to an embolic plaque, which was successfully treated with tissue plasminogen activator and intravenous heparin.


English

1878-0938

10.1016/j.carrev.2020.04.029 [doi] S1553-8389(20)30235-9 [pii]


*Aorta, Thoracic
*Brachiocephalic Trunk
*Carotid Stenosis/th [Therapy]
*Endovascular Procedures
*Lithotripsy
*Subclavian Artery
*Vascular Calcification/th [Therapy]
Aged
Aged, 80 and over
Aorta, Thoracic/dg [Diagnostic Imaging]
Brachiocephalic Trunk/dg [Diagnostic Imaging]
Carotid Stenosis/dg [Diagnostic Imaging]
Endovascular Procedures/ae [Adverse Effects]
Humans
Lithotripsy/ae [Adverse Effects]
Male
Middle Aged
Retrospective Studies
Severity of Illness Index
Subclavian Artery/dg [Diagnostic Imaging]
Treatment Outcome
Vascular Calcification/dg [Diagnostic Imaging]


MedStar Heart & Vascular Institute


Journal Article