TY  - BOOK
AU  - Garcia-Garcia, Hector M
AU  - Mintz, Gary S
AU  - Ozaki, Yuichi
AU  - Waksman, Ron
TI  - Supporting evidence from optical coherence tomography for shortening dual antiplatelet therapy after drug-eluting stents implantation. [Review]
SN  - 1477-9072
PY  - 2020///
KW  - *Drug-Eluting Stents
KW  - *Platelet Aggregation Inhibitors/ad [Administration & Dosage]
KW  - *Tomography, Optical Coherence/mt [Methods]
KW  - Coronary Artery Disease/th [Therapy]
KW  - Hemorrhage/ci [Chemically Induced]
KW  - Humans
KW  - Neointima
KW  - Thrombosis/et [Etiology]
KW  - Treatment Outcome
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
N2  - Introduction: Dual antiplatelet therapy (DAPT) is required for coronary artery disease treated with drug-eluting stents (DES) implantation. Shortening DAPT duration would be beneficial for patients with high bleeding risk. Areas covered: Early healing patterns, especially stent strut coverage, assessed by optical coherence tomography (OCT) as a surrogate of neointima have been investigated to make decisions on whether short DAPT would be a safe alternative. This review evaluates the OCT evidence (i.e. neointimal coverage of stent struts within 3 months) for shortening DAPT duration after DES implantation. Expert commentary: Shortening DAPT (i.e. within 3 months) duration after DES implantation might reduce complications including bleeding without increasing stent thrombosis. However, the optimal duration of DAPT after DES implantation is under discussion. Long-term assessment of short DAPT is required for the decision of the new guidelines regarding the recommended duration of DAPT
UR  - https://dx.doi.org/10.1080/14779072.2020.1759421
ER  -