TY  - BOOK
AU  - Wartofsky, Leonard
TI  - Bone metastasis from noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP); a case report
SN  - 1472-6823
PY  - 2021///
KW  - *Adenocarcinoma, Follicular/sc [Secondary]
KW  - *Bone Neoplasms/sc [Secondary]
KW  - *Thyroid Neoplasms/pa [Pathology]
KW  - *Thyroid Nodule/pa [Pathology]
KW  - Adenocarcinoma, Follicular/dg [Diagnostic Imaging]
KW  - Adenocarcinoma, Follicular/rt [Radiotherapy]
KW  - Adult
KW  - Bone Neoplasms/dg [Diagnostic Imaging]
KW  - Bone Neoplasms/rt [Radiotherapy]
KW  - Cell Nucleus/pa [Pathology]
KW  - Female
KW  - Humans
KW  - Ilium/dg [Diagnostic Imaging]
KW  - Iodine Radioisotopes/tu [Therapeutic Use]
KW  - Single Photon Emission Computed Tomography Computed Tomography
KW  - Thyroid Cancer, Papillary/pa [Pathology]
KW  - Thyroid Neoplasms/su [Surgery]
KW  - Thyroid Nodule/su [Surgery]
KW  - Thyroidectomy
KW  - Tomography, X-Ray Computed
KW  - MedStar Health Research Institute
KW  - Case Reports
KW  - Journal Article
N1  - Available online from MWHC library: 2001 - present
N2  - BACKGROUND: The term non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was recently proposed as a non-malignant thyroid lesion with indolent behavior that does not require post-operative radio-iodine treatment. We are reporting a case of NIFTP with bone metastasis that is the second case reported so far; CASE PRESENTATION: We describe a 38-year-old woman who presented with an indeterminate thyroid nodule and underwent total thyroidectomy with the finding of NIFTP on careful pathologic examination. However, her initial follow-up evaluation revealed a serum thyroglobulin level of > 300 ng/ml and a diagnostic whole body 131I scan demonstrated a focus of increased uptake in the left hemipelvis, confirmed on CT scan to be a lytic lesion in the left iliac bone. She was treated with 7.4GBq (200 mCi) of 131I and her follow-up 1 year later revealed an undetectable serum thyroglobulin and a negative whole body 131I scan with no visible uptake in the iliac bone indicating an excellent response; CONCLUSION: This case presentation reminds us to be alert to the rare occurrence of distant metastasis in NIFTP and the need for a case by case analysis and continuing post-operative follow-up for detection of residual or recurrent disease. Copyright © 2021. The Author(s)
UR  - https://dx.doi.org/10.1186/s12902-021-00883-7
ER  -