TY  - BOOK
AU  - Howard, Barbara V
AU  - Umans, Jason G
TI  - Ten-year weight gain is not associated with multiple cardiometabolic measures in Alaska EARTH study participants
SN  - 0939-4753
PY  - 2021///
KW  - *Alaskan Natives
KW  - *Body-Weight Trajectory/eh [Ethnology]
KW  - *Obesity/eh [Ethnology]
KW  - *Weight Gain/eh [Ethnology]
KW  - Adult
KW  - Alaska/ep [Epidemiology]
KW  - Cardiometabolic Risk Factors
KW  - Female
KW  - Humans
KW  - Longitudinal Studies
KW  - Male
KW  - Middle Aged
KW  - Obesity/di [Diagnosis]
KW  - Obesity/pp [Physiopathology]
KW  - Prospective Studies
KW  - Risk Assessment
KW  - Sex Factors
KW  - Time Factors
KW  - MedStar Health Research Institute
KW  - Journal Article
N2  - BACKGROUND AND AIMS: Alaska Native (AN) traditional lifestyle may be protective against chronic disease risk. Weight gain in adulthood has been linked to increases in chronic disease risk among other populations; yet, its impact among Alaska Native people has never been evaluated. We aimed to evaluate changes in obesity-related metrics over time, and determine associations of changes with cardiometabolic markers of chronic disease risk among AN people; CONCLUSIONS: While weight increase over a 10-year period was not associated with substantive changes in cardiometabolic measures among AN men, there was a decrease in high density lipid cholesterol associated with weight gain among AN women. Copyright (c) 2020 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved; METHODS AND RESULTS: Study participants enrolled in the southcentral Alaska Education and Research Towards Health Study in 2004-2006 were invited to participate in a follow-up study conducted 2015-2017. Of the original 1320 participants, 388 completed follow-up health assessments consisting of multiple health surveys, anthropometric measurements, and cardiometabolic measures including blood sugars, blood lipids, and blood pressure. Differences in measurements between visits were determined and associations of weight change with cardiometabolic measures evaluated. Body mass index increased by 3.7 kg/m2 among men and 4.8 kg/m2 among women. Hip circumference (1.1 cm, p < 0.01) and waist circumference (0.7 cm, p < 0.01) increased among women; only waist circumference increased among men (1.6 cm, p < 0.01). Among men, there were no associations of weight change with cardiometabolic measures. Among women, there was an inverse association between weight gain and high-density lipoprotein cholesterol only (0.17 mg/dL (CI: -3.1, -0.03), p = 0.02)
UR  - https://dx.doi.org/10.1016/j.numecd.2020.09.022
ER  -