TY - BOOK AU - Zerah, Michele L TI - Cutaneous Keratocyst With D2-40 Immunoreactivity in Basal Cell Nevus Syndrome SN - 0193-1091 PY - 2021/// KW - *Basal Cell Nevus Syndrome/me [Metabolism] KW - *Epidermal Cyst/me [Metabolism] KW - *Membrane Glycoproteins/me [Metabolism] KW - *Skin Neoplasms/me [Metabolism] KW - Antibodies, Monoclonal, Murine-Derived KW - Basal Cell Nevus Syndrome/pa [Pathology] KW - Child KW - Female KW - Humans KW - Odontogenic Cysts/me [Metabolism] KW - Skin Neoplasms/pa [Pathology] KW - MedStar Washington Hospital Center KW - Dermatology KW - Journal Article N1 - Available online from MWHC library: Feb 1996 - present N2 - ABSTRACT: Although not a diagnostic criterion for basal cell nevus syndrome (BCNS, OMIM#109400), cutaneous cysts, particularly epidermoid cysts, are common in this condition. Cutaneous keratocysts, on the other hand, are extremely rare in general and have been identified in only 5 patients with BCNS. Here, we describe a BCNS patient with a cutaneous keratocyst that demonstrated D2-40 (podoplanin) immunoreactivity, which has been detected in odontogenic keratocysts but not cutaneous keratocysts. This finding suggests that cutaneous keratocysts may be developmentally homologous to odontogenic keratocysts and may behave similarly in terms of invasion and growth pattern. Copyright (c) 2021 Wolters Kluwer Health, Inc. All rights reserved UR - https://dx.doi.org/10.1097/DAD.0000000000001638 ER -