03149nam a22004577a 4500
211101s20212021 xxu||||| |||| 00| 0 eng d
0742-2822
Ovid MEDLINE(R)
34555211
Right ventricular free wall strain in acutely decompensated heart failure patients with ischemic and non-ischemic cardiomyopathy.
Echocardiography. 38(10):1747-1753, 2021 10.
Echocardiography. 38(10):1747-1753, 2021 10.
Echocardiography. 2021 Sep 23
Echocardiography (Mount Kisco, N.Y.)
2021
FY2022
aheadofprint
ppublish
2021-11-01
Echocardiography. 2021 Sep 23
FY2022
AIMS: Right ventricular (RV) dysfunction is a predictor of adverse outcomes among patients with HF with reduced ejection fraction (HFrEF); however, differences in RV parameters in HFrEF patients with ischemic (ICM) and non-ischemic cardiomyopathies (NICM) are not well understood. We investigated echocardiographic characteristics, including RV strain, in patients with acute decompensated heart failure (ADHF) and compared patients with ICM and NICM etiology.
CONCLUSION: Among patients hospitalized with ADHF, patients with nonischemic etiology compared with the patients with ICM, have more severe RV dysfunction measured by RVfwLS, despite similar extent of LV impairment and the same functional limitation class. Copyright (c) 2021 Wiley Periodicals LLC.
METHODS: Consecutive patients who presented with ADHF and NYHA class III-IV were prospectively enrolled if they had LVEF < 40% and history of ICM or NICM. All patients underwent clinical exam, laboratory evaluation and 2-D echocardiographic assessment of the left ventricular (LV) and RV function, LV and RV global longitudinal strain (LVGLS, RVGLS), and RV free wall strain (RVfwLS).
RESULTS: Of 84 patients, 44 had ICM and 40 NICM. The groups had similar blood pressure, NT-proBNP, and echocardiographic parameters of LV function including LVGLS. Absolute RVGLS values were lower than RVfwLS values in both groups. Patients with NICM had significantly lower RVfwLS, but not RVGLS, compared to patients with ICM (-13% to -17%, p = 0.006). Similar differences in RVfwLS were seen in patients in NYHA class III (NICM vs ICM: -13% and -17%, respectively, 95% CI: -8.5 to -.5) and NYHA class IV (NICM vs ICM: -13.8% and -17%, respectively, 95% CI: -6.4 to -.59).
English
*Cardiomyopathies
*Heart Failure
*Myocardial Ischemia
Heart Failure/co [Complications]
Heart Failure/dg [Diagnostic Imaging]
Humans
Stroke Volume
Ventricular Function, Right
MedStar Heart & Vascular Institute
Journal Article
Barac, Ana
Bakovic D, Barac A, Capkun V, Miric D
https://dx.doi.org/10.1111/echo.15205
https://dx.doi.org/10.1111/echo.15205
ART
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authcat
authcat
2021-11-01
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34555211
34555211
2021-11-01
2021-11-01
ART
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