TY  - BOOK
AU  - Gandhi, Kejal
AU  - Kim, Jeffrey
AU  - Lee, Zone-en
AU  - Smith, Hedy P
AU  - Vobugari, Nikitha
TI  - Iron-Storage Disorder Presenting as Chronic Diarrhea
SN  - 2168-8184
PY  - 2021///
KW  - IN PROCESS -- NOT YET INDEXED
KW  - MedStar Washington Hospital Center
KW  - Gastroenterology Fellowship
KW  - Hematology and Oncology
KW  - Internal Medicine Residency
KW  - Medicine/Gastroenterology
KW  - MedStar General Surgery Residency
KW  - Case Reports
N2  - The involvement of the endocrine pancreas leading to bronze diabetes is well studied. However, little is known about the pathophysiology of iron dysregulation involving the exocrine pancreas. We present a unique association between the exocrine pancreas and iron dysregulation. A 45-year-old female presented with chronic diarrhea and low fecal elastase indicative of pancreatic exocrine dysfunction. MRI of the abdomen/pelvis showed iron deposition in the pancreas, suggesting an associated iron-storage disorder without features suggesting chronic pancreatitis. Association of an iron-storage disorder with pancreatic exocrine dysfunction has been reported only in one other case report. Pancreatic exocrine dysfunction can be directly associated with an iron-storage disorder that involves the pancreas. This should be included in the differential and diagnostic work-up of chronic diarrhea of unclear etiology. Based on the literature, we have highlighted the potential pathophysiology relevant to the case. Copyright (c) 2021, Vobugari et al
UR  - https://dx.doi.org/10.7759/cureus.18864
ER  -