TY - BOOK AU - Pahuja, Mohit TI - Device profile of the Impella 5.0 and 5.5 system for mechanical circulatory support for patients with cardiogenic shock: overview of its safety and efficacy SN - 1743-4440 PY - 2022/// KW - *Extracorporeal Membrane Oxygenation KW - *Heart Failure KW - *Heart-Assist Devices KW - Heart Failure/et [Etiology] KW - Heart Failure/su [Surgery] KW - Heart-Assist Devices/ae [Adverse Effects] KW - Humans KW - Intra-Aortic Balloon Pumping/ae [Adverse Effects] KW - Shock, Cardiogenic/su [Surgery] KW - Treatment Outcome KW - MedStar Washington Hospital Center KW - Advanced Heart Failure and Transplant Cardiology Fellowship KW - Journal Article N2 - AREAS COVERED: This review focuses on the device profile and use of the Impella 5.0 and 5.5 systems in patients with CS. Specifically; we reviewed the published literature for Impella 5.0 device to summarize data regarding safety and efficacy; EXPERT OPINION: The Impella 5.0 and 5.5 are trans-valvular micro-axial flow pumps for which the current data suggest excellent safety and efficacy profiles as approaches to provide circulatory support, myocardial unloading, and axillary placement enabling patient mobilization and rehabilitation; INTRODUCTION: Trans-valvular micro-axial flow pumps such as Impella are increasingly utilized in patients with cardiogenic shock [CS]. A number of different Impella devices are now available providing a wide range of cardiac output. Among these, the Impella 5.0 and recently introduced Impella 5.5 pumps can provides 5.55 L/min of flow, enabling complete left ventricular support with more favorable hemodynamic effects on myocardial oxygen consumption and left ventricular unloading. These devices require placement of a surgical conduit graft for endovascular delivery, but are increasingly being used in patients with CS due to acutely decompensated heart failure [ADHF], acute myocardial infarction [AMI] and after cardiac surgery as a bridge to transplant or durable ventricular assist device surgery or myocardial recovery UR - https://dx.doi.org/10.1080/17434440.2022.2015323 ER -