A prospective study evaluating emotional disturbance in subjects undergoing defecating proctography.

MedStar author(s):
Citation: World Journal of Gastroenterology. 19(25):3990-5, 2013 Jul 7.PMID: 23840143Institution: MedStar Washington Hospital CenterDepartment: Medicine/Gastroenterology | RadiologyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Affective Symptoms/ep [Epidemiology] | *Colorectal Surgery/mt [Methods] | *Constipation/pp [Physiopathology] | *Constipation/px [Psychology] | *Defecography/mt [Methods] | *Gastrointestinal Diseases/pp [Physiopathology] | *Gastrointestinal Diseases/px [Psychology] | Affective Symptoms/di [Diagnosis] | Aged | Anxiety/di [Diagnosis] | Anxiety/ep [Epidemiology] | Cohort Studies | Depression/di [Diagnosis] | Depression/ep [Epidemiology] | Female | Humans | Male | Mass Screening | Middle Aged | Prevalence | Prospective Studies | Psychology | Questionnaires | Reproducibility of Results | Severity of Illness Index | Sex Offenses/px [Psychology] | Stress Disorders, Post-Traumatic/di [Diagnosis] | Stress Disorders, Post-Traumatic/ep [Epidemiology]ISSN:
  • 1007-9327
Name of journal: World journal of gastroenterology : WJGAbstract: AIM: To investigate the prevalence of psychiatric illness in association with functional gastrointestinal disorders using defecating proctography (DP) and validated questionnaires.CONCLUSION: The findings of this prospective study demonstrate a significantly high degree of psychiatric ailments in patients with negative findings on DP who should be appropriately screened for a history of sexual abuse and symptoms of psychosocial distress.METHODS: We prospectively evaluated 45 subjects referred for DP using hospital anxiety and depression scale (HADS), state trait anxiety inventory (STAI), patient health questionnaire 15-item somatic symptom severity scale (PHQ-15), validated questionnaires for sexual or physical abuse; post-traumatic stress disorder questionnaire (PTSD) and ROME-III questionnaires for gastrointestinal complaints. DP results were considered negative if levator ani function was normal, rectoceles (if any) were < 4 cm and there was no evidence of intussusception, rectal prolapse, or other anatomic abnormality demonstrated. Subjects were subsequently divided into those with structural defects seen on DP (DP positive group) and those with a normal defecography study (DP negative group).RESULTS: Forty five subjects were included in the study of which 20 subjects were classified as DP negative (44.4%). There was a striking prevalence of a history of sexual abuse in DP negative group compared to the DP positive group (n = 9, 5 respectively; P = 0.036). Further, subjects in the DP negative group scored significantly higher on the HADS anxiety (6.60 + 1.00 vs 4.72 + 0.40, P = 0.04) and depression scales (5.72 + 1.00 vs 3.25 + 0.46, P = 0.01). This correlated well with significantly higher scores on the STAI state anxiety scale (42.75 + 3.16 vs 35.6 + 2.00, P = 0.027), PHQ-15 questionnaire (13.15 + 0.82 vs 10.76 + 0.97, P = 0.038) and prevalence of PTSD (20% vs 4%, P = 0.045) among DP negative subjects. There was no difference between the groups in terms of STAI trait anxiety.All authors: Kashyap AS, Kohli DR, Olden KW, Raizon ADigital Object Identifier: Date added to catalog: 2014-04-03
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article Available 23840143

AIM: To investigate the prevalence of psychiatric illness in association with functional gastrointestinal disorders using defecating proctography (DP) and validated questionnaires.

CONCLUSION: The findings of this prospective study demonstrate a significantly high degree of psychiatric ailments in patients with negative findings on DP who should be appropriately screened for a history of sexual abuse and symptoms of psychosocial distress.

METHODS: We prospectively evaluated 45 subjects referred for DP using hospital anxiety and depression scale (HADS), state trait anxiety inventory (STAI), patient health questionnaire 15-item somatic symptom severity scale (PHQ-15), validated questionnaires for sexual or physical abuse; post-traumatic stress disorder questionnaire (PTSD) and ROME-III questionnaires for gastrointestinal complaints. DP results were considered negative if levator ani function was normal, rectoceles (if any) were < 4 cm and there was no evidence of intussusception, rectal prolapse, or other anatomic abnormality demonstrated. Subjects were subsequently divided into those with structural defects seen on DP (DP positive group) and those with a normal defecography study (DP negative group).

RESULTS: Forty five subjects were included in the study of which 20 subjects were classified as DP negative (44.4%). There was a striking prevalence of a history of sexual abuse in DP negative group compared to the DP positive group (n = 9, 5 respectively; P = 0.036). Further, subjects in the DP negative group scored significantly higher on the HADS anxiety (6.60 + 1.00 vs 4.72 + 0.40, P = 0.04) and depression scales (5.72 + 1.00 vs 3.25 + 0.46, P = 0.01). This correlated well with significantly higher scores on the STAI state anxiety scale (42.75 + 3.16 vs 35.6 + 2.00, P = 0.027), PHQ-15 questionnaire (13.15 + 0.82 vs 10.76 + 0.97, P = 0.038) and prevalence of PTSD (20% vs 4%, P = 0.045) among DP negative subjects. There was no difference between the groups in terms of STAI trait anxiety.

English

Powered by Koha