000			02872nam a22004097a 4500
008			210726s20212021 xxu||||| |||| 00| 0 eng d
024			_a10.3390/cancers13122964 [doi]
024			_acancers13122964 [pii]
024			_aPMC8231850 [pmc]
040			_aOvid MEDLINE(R)
099			_a34199234
245			_aThe Characteristics of 206 Long-Term Survivors with Peritoneal Metastases from Colorectal Cancer Treated with Curative Intent Surgery: A Multi-Center Cohort from PSOGI.
251			_aCancers. 13(12), 2021 Jun 13.
252			_aCancers (Basel). 13(12), 2021 Jun 13.
253			_aCancers
260			_c2021
260			_fFY2021
260			_p2021 Jun 13
265			_sepublish
266			_d2021-07-26
520			_aBACKGROUND: We conducted this study to review the patient characteristics associated with long-term survival in patients with peritoneal metastases from colorectal cancer who underwent cytoreductive surgery (CRS).
520			_aCONCLUSIONS: While most long-term survivors showed low PCI/SB-PCI and CCR-0, some had characteristics considered associated with poor prognosis. Curative intent treatments may be considered in well-informed and fit patients showing negative factors affecting survival outcome.
520			_aMETHODS: We retrospectively investigated patients with peritoneal metastases from CRC treated with curative intent surgery with or without hyperthermic intraperitoneal chemotherapy at 13 institutions worldwide between January 1985 and April 2015 and survived longer than five years after the first CRS for peritoneal metastases. Clinical and oncological features and therapeutic parameters were described and analyzed.
520			_aRESULTS: Two hundred six long-term survivors were available for study. The median peritoneal cancer index (PCI) of this cohort was 4 (interquartile range (IQR), 2-7), and the median score of the small bowel regions of the PCI (SB-PCI) was 0 (IQR, 0-2). Complete cytoreduction (CC-0) was achieved in 180 (87.4%) patients. Recurrence was observed in 122 (59.2%) patients at a median of 1.8 (IQR, 1.2-2.6) years.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Washington Hospital Center
651			_aWashington Cancer Institute
656			_aMedStar General Surgery Residency
657			_aJournal Article
700			_aGhabra, Shadin
700			_aSugarbaker, Paul H
790			_aAcs M, Bhatt A, Bonnot PE, Canbay E, Coccolini F, Ghabra S, Glehen O, Goi T, Hida K, Hsieh MC, Ishihara S, Kamada Y, Katayama K, Morikawa M, Murono K, Nagata H, Piso P, Rau B, Sugarbaker PH, Yonemura Y
856			_uhttps://dx.doi.org/10.3390/cancers13122964 _zhttps://dx.doi.org/10.3390/cancers13122964
858			_yGhabra, Shadin _uhttps://orcid.org/0000-0002-1505-2992 _zhttps://orcid.org/0000-0002-1505-2992
942			_cART _dArticle
999			_c10832 _d10832