000 03257nam a22003737a 4500
008 201229s20202020 xxu||||| |||| 00| 0 eng d
040 _aOvid MEDLINE(R)
099 _a33014480
245 _aGastric Mucormycosis: An Infection of Fungal Invasion into the Gastric Mucosa in Immunocompromised Patients.
251 _aCase Reports in Gastrointestinal Medicine. 2020:8876125, 2020.
252 _aCase Rep Gastrointest Med. 2020:8876125, 2020.
253 _aCase reports in gastrointestinal medicine
260 _c2020
260 _fFY2021
265 _sepublish
266 _d2020-12-29
520 _aPrimary gastric mucormycosis is a rare but potentially lethal fungal infection due to the invasion of Mucorales into the gastric mucosa. It may result in high mortality due to increased risk of complications in immunocompromised patients. Common predisposing risk factors to develop gastric mucormycosis are prolonged uncontrolled diabetes mellitus with or without diabetic ketoacidosis (DKA), solid organ or stem cell transplantation, underlying hematologic malignancy, and major trauma. Abdominal pain, hematemesis, and melena are common presenting symptoms. The diagnosis of gastric mucormycosis can be overlooked due to the rarity of the disease. A high index of suspicion is required for early diagnosis and management of the disease, particularly in immunocompromised patients. Radiological imaging findings are nonspecific to establish the diagnosis, and gastric biopsy is essential for histological confirmation of mucormycosis. Prompt treatment with antifungal therapy is the mainstay of treatment with surgical resection reserved in cases of extensive disease burden or clinical deterioration. We presented a case of acute gastric mucormycosis involving the body of stomach in a patient with poorly controlled diabetes and chronic renal disease, admitted with acute onset of abdominal pain. Complete resolution of lesion was noted with 16 weeks of medical treatment with intravenous amphotericin B and posaconazole. Copyright (c) 2020 Haider A. Naqvi et al.
546 _aEnglish
650 _aIN PROCESS -- NOT YET INDEXED
651 _aMedStar Franklin Square Medical Center
651 _aMedStar Union Memorial Hospital
656 _aDepartment of Gastroenterology
656 _aMedicine
657 _aCase Reports
700 _aChaudhary, Fizah S
700 _aMills, Lawrence
700 _aNadeem Yousaf, Muhammad
700 _aNaqvi, Haider A
790 _aChaudhary FS, Mills L, Nadeem Yousaf M, Naqvi HA
856 _uhttps://dx.doi.org/10.1155/2020/8876125
_zhttps://dx.doi.org/10.1155/2020/8876125
858 _yNadeem Yousaf, Muhammad
_yNaqvi, Haider A
_uhttps://orcid.org/0000-0002-7979-8929
_uhttps://orcid.org/0000-0001-5722-533X
_zhttps://orcid.org/0000-0002-7979-8929
_zhttps://orcid.org/0000-0001-5722-533X
_zhttps://orcid.org/0000-0002-7979-8929
_zhttps://orcid.org/0000-0001-5722-533X
858 _yNadeem Yousaf, Muhammad
_yNaqvi, Haider A
_uhttps://orcid.org/0000-0002-7979-8929
_uhttps://orcid.org/0000-0001-5722-533X
_zhttps://orcid.org/0000-0002-7979-8929
_zhttps://orcid.org/0000-0001-5722-533X
_zhttps://orcid.org/0000-0002-7979-8929
_zhttps://orcid.org/0000-0001-5722-533X
942 _cART
_dArticle
999 _c10878
_d10878