000			03228nam a22005177a 4500
008			140821s20142014 xxu||||| |||| 00| 0 eng d
022			_a0015-0282
040			_aOvid MEDLINE(R)
099			_a24269042
245			_aOvarian reserve and subsequent assisted reproduction outcomes after methotrexate therapy for ectopic pregnancy or pregnancy of unknown location.
251			_aFertility & Sterility. 101(2):413-9, 2014 Feb.
252			_aFertil Steril. 101(2):413-9, 2014 Feb.
253			_aFertility and sterility
266			_d2014-08-21
501			_aAvailable online from MWHC library: 1997 - present, Available in print through MWHC library:1999-2007
520			_aCONCLUSION(S): Ovarian reserve and subsequent ART cycle outcomes were reassuring after methotrexate or surgical management of ectopic pregnancy. No adverse impact of methotrexate was detected in this large fertility cohort as has been previously described elsewhere. Published by Elsevier Inc.
520			_aDESIGN: Retrospective cohort study.
520			_aINTERVENTION(S): None.
520			_aMAIN OUTCOME MEASURE(S): Follicle-stimulating hormone (FSH), antral follicle count (AFC), and oocyte yield compared between women treated with methotrexate or surgery, with secondary outcomes of clinical pregnancy and live birth.
520			_aOBJECTIVE: To assess ovarian reserve after methotrexate treatment for ectopic pregnancy or pregnancy of unknown location after assisted reproductive technology (ART).
520			_aPATIENT(S): Women receiving methotrexate or surgery after ART.
520			_aRESULT(S): There were 153 patients in the methotrexate group and 36 patients in the surgery group. Neither group demonstrated differences in ovarian reserve or oocyte yield in a comparison of the before and after treatment values. The 20140821 in ovarian reserve and oocyte yield after treatment were similar between the two groups. The number of doses of methotrexate was not correlated with 140821s in ovarian reserve, indicating no dose-dependent effect. Time between treatment and repeat ART was not correlated with outcomes. Live birth in subsequent cycles was similar in the two groups.
520			_aSETTING: Large ART practice.
546			_aEnglish
650			_a*Methotrexate/tu [Therapeutic Use]
650			_a*Oocyte Retrieval/td [Trends]
650			_a*Pregnancy, Ectopic/dt [Drug Therapy]
650			_a*Pregnancy, Ectopic/su [Surgery]
650			_a*Reproductive Techniques, Assisted/td [Trends]
650			_aAdult
650			_aCohort Studies
650			_aFemale
650			_aHumans
650			_aPregnancy
650			_aPregnancy, Ectopic/di [Diagnosis]
650			_aRetrospective Studies
650			_aTreatment Outcome
651			_aMedStar Washington Hospital Center
656			_aObstetrics and Gynecology
657			_aJournal Article
657			_aResearch Support, N.I.H., Extramural
700			_aCooper, Janelle
790			_aAlford C, Cooper JC, DeCherney AH, Hill MJ, Katz CL, Levens ED, Levy G, Richter KS, Wolff EF
856			_uhttp://dx.doi.org/10.1016/j.fertnstert.2013.10.027 _zhttp://dx.doi.org/10.1016/j.fertnstert.2013.10.027
942			_cART _dJournal article
999			_c12261 _d12261