000 02471nam a22004697a 4500
008 2401116s20232023 xxu||||| |||| 00| 0 eng d
022 _a1757-790X
024 _a10.1136/bcr-2023-256579 [doi]
024 _a16/12/e256579 [pii]
040 _aOvid MEDLINE(R)
099 _a38087480
245 _aGreat mimicker: definite isolated cardiac sarcoidosis masquerading as hypertrophic cardiomyopathy.
251 _aBMJ Case Reports. 16(12), 2023 Dec 09.
252 _aBMJ Case Rep. 16(12), 2023 Dec 09.
253 _aBMJ case reports
260 _c2023
260 _fFY2024
260 _p2023 Dec 09
265 _sepublish
265 _tPubMed-not-MEDLINE
266 _d2024-01-16
520 _aA healthy man in his 50s was hospitalised after presenting with chest pain and dyspnoea. An echocardiogram revealed asymmetrical septal hypertrophy, leading to a diagnosis of hypertrophic cardiomyopathy. Due to progressive conduction abnormalities during his hospitalisation, further evaluation was performed. Cardiac MRI revealed dense late gadolinium enhancement of the septum in the area of hypertrophy. Additionally, fluorodeoxyglucose-positron emission tomography demonstrated increased uptake within the same region, suggestive of active inflammation. Subsequent endomyocardial biopsy showed non-caseating granulomatous inflammation, consistent with cardiac sarcoidosis. Treatment with prednisone and methotrexate was initiated, and an implantable cardioverter-defibrillator was placed following thorough risk stratification. This case highlights the importance of multimodality imaging and the pursuit of a tissue diagnosis in the evaluation of cardiomyopathy. Copyright © BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.
546 _aEnglish
650 _a*Cardiomyopathy, Hypertrophic
650 _a*Myocarditis
650 _a*Sarcoidosis
650 _aCardiomyopathy, Hypertrophic/dg [Diagnostic Imaging]
650 _aContrast Media
650 _aGadolinium
650 _aHumans
650 _aHypertrophy
650 _aInflammation
650 _aMale
650 _aSarcoidosis/pa [Pathology]
651 _aMedStar Heart & Vascular Institute
657 _aCase Reports
657 _aJournal Article
700 _aSheikh, Farooq H
_bMHVI
790 _aPham T, Abraham J, Sheikh FH
856 _uhttps://dx.doi.org/10.1136/bcr-2023-256579
942 _cART
_dArticle
999 _c13713
_d13713