000 03556nam a22003977a 4500
008 240424s20242024 xxu||||| |||| 00| 0 eng d
022 _a0890-5096
024 _aS0890-5096(24)00051-7 [pii]
040 _aOvid MEDLINE(R)
099 _a38387800
245 _aRisk Factors for Lower Extremity Minor Amputation Conversion to Major Amputation.
251 _aAnnals of Vascular Surgery. 104:166-173, 2024 Feb 20.
252 _aAnn Vasc Surg. 104:166-173, 2024 Feb 20.
253 _aAnnals of vascular surgery
260 _c2024
260 _fFY2024
260 _p2024 Feb 20
265 _saheadofprint
265 _tPublisher
266 _d2024-04-24
501 _aAvailable online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007
520 _aBACKGROUND: Minor lower extremity amputations (LEAs) have become an important part of the limb salvage approach but are not as benign as previously thought. This study investigates the difference in outcome between toe/ray versus midfoot amputations and the risk factors for major amputation conversion associated with each procedure.
520 _aCONCLUSIONS: While there is a consistency with previous studies that found no significant overall difference in mortality between types of minor LEA, we have extended this previous work by demonstrating the independent risk factors for conversion to major amputation between types of minor LEA. Comparing these 2 groups will assist surgeons in choosing the appropriate level of amputations and will enhance patient's understanding of their chance of wound healing and risk of repeat amputation. Copyright © 2024 Elsevier Inc. All rights reserved.
520 _aMETHODS: We performed retrospective chart review of foot amputation patients at a single tertiary care medical center with a primary end point of conversion to major amputation and secondary end points of 1-year wound healing and mortality rate. We collected data on relevant medical comorbidities, noninvasive vascular imaging, revascularization, repeat amputations, wound healing rate, and 1-year mortality. Patients were separated into toe/ray amputations versus midfoot amputation groups and compared using descriptive statistics, Chi-squared tests, Cox proportional hazards, and a multivariate logistic regression model.
520 _aRESULTS: A total of 375 amputations were included in the analysis. 65.3% (245 patients) included toe/ray amputations and 34.7% (130 patients) included midfoot amputations. We compared these 2 cohorts with regard to their rate of conversion to repeat minor and/or major amputation in addition to overall mortality. The toe/ray group underwent more repeat minor amputations within 1 year after index amputation (34.7% vs. 21.5%, P = 0.008) and wound healing (epithelization) at 90 days was also higher in this group. The midfoot group had a higher conversion to major LEA within 1 year on univariate analysis (20.8 vs. 6.9%, P < 0.001). Overall 1-year mortality was 6.17% and there was no significant difference between groups.
546 _aEnglish
650 _aIN PROCESS -- NOT YET INDEXED
650 _zAutomated
651 _aMedStar Franklin Square Medical Center
656 _aGeneral Surgery Residency
657 _aJournal Article
700 _aKawaji, Qingwen
_bMFSMC
_cGeneral Surgery Residency
_dMD
790 _aRolle NP, Kawaji Q, Morton C, Rosenberg KM, Kalsi R, Blitzer DN, Nagarsheth K
856 _uhttps://dx.doi.org/10.1016/j.avsg.2023.12.066
942 _cART
_dArticle
999 _c14083
_d14083