000			03990nam a22004457a 4500
008			240807s20242024 xxu||||| |||| 00| 0 eng d
022			_a1079-2082
024			_a7683012 [pii]
040			_aOvid MEDLINE(R)
099			_a38800925
245			_aThe empty code cart: Drug shortages over time.
251			_aAmerican Journal of Health-System Pharmacy. 2024 May 27
252			_aAm J Health-Syst Pharm. 2024 May 27
253			_aAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
260			_c2024
260			_fFY2024
260			_p2024 May 27
265			_saheadofprint
265			_tPublisher
266			_d2024-08-07
266			_z2024/05/27 05:18
501			_aAvailable online through MWHC library: 2002 - 2010, Available in print through MWHC library: 2010 - present
520			_aCONCLUSION: Medications commonly used in code carts were frequently impacted by drug shortages, which have the potential to impact patient care. Institutional protocols for mitigation and larger efforts to promote a more resilient drug supply chain are critical to ensure patient safety and quality care. Copyright © American Society of Health-System Pharmacists 2024. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site-for further information please contact [email protected].
520			_aDISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.
520			_aMETHODS: Drug shortage data from 2001 to 2022 were retrieved from the University of Utah Drug Information Service (UUDIS) to characterize shortages reported for commonly used code cart medications. Data extracted included the number of shortages, shortage duration, drug characteristics, and reason for the shortage.
520			_aPURPOSE: In high-acuity situations such as cardiac arrest, clinicians rely on prepared medications stocked in code carts to provide timely and accurate pharmacotherapy. We examined shortage trends for medications commonly used in code carts.
520			_aRESULTS: From 2001 to 2022, 71 drug shortages for code cart medications were reported. The number of new shortages peaked in 2010, and the number of total shortages peaked in 2010. At the end of the study period, 61 (84.7%) shortages had been resolved. For resolved shortages, the mean shortage duration was 18.2 months. The drug with the greatest number of reported shortages was dextrose (10 total), the drug with the longest resolved shortage was calcium chloride injection (116 months), and the drug with the longest active shortage was atropine injection (165 months at the end of the study period). Throughout the entire study period, only 2 suppliers provided commercially available prefilled syringes of dextrose for stocking on code carts. The most common reason for shortages, when reported, was manufacturing delays.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
650			_zAutomated
651			_aMedStar Washington Hospital Center
656			_aEmergency Medicine
656			_aNursing
657			_aJournal Article
700			_aHeinrichs, Dorothy _bMWHC
700			_aHockstein, Max A _bMWHC
790			_aGentile T, Snee I, Heinrichs D, Hockstein MA, Mazer-Amirshahi M, Fox ER
856			_uhttps://dx.doi.org/10.1093/ajhp/zxae150 _zhttps://dx.doi.org/10.1093/ajhp/zxae150
942			_cART _dArticle
999			_c14411 _d14411