000			03934nam a22004817a 4500
008			240807s20242024 xxu||||| |||| 00| 0 eng d
022			_a2667-2960
024			_aS2667-2960(24)00048-X [pii]
040			_aOvid MEDLINE(R)
099			_a38705515
245			_aPrognostic Implications of Delirium After Left Ventricular Assist Device Implantation: A Retrospective Study.
251			_aJournal of the Academy of Consultation-Liaison Psychiatry. 2024 May 03
252			_aJ Acad Consult Liaison Psychiatry. 2024 May 03
253			_aJournal of the Academy of Consultation-Liaison Psychiatry
260			_c2024
260			_fFY2024
260			_p2024 May 03
265			_saheadofprint
265			_tPublisher
266			_d2024-08-07
266			_z2024/05/05 19:31
520			_aBACKGROUND: In critically ill patients, delirium is a prognostic indicator of morbidity and mortality.
520			_aCONCLUSIONS: In this study, a diagnosis of delirium during the LVAD implantation admission was associated with higher mortality, adverse postsurgical outcomes, and unfavorable discharge dispositions. Future prospective research is needed to validate the prognostic implications of delirium in both the short and long term. Additionally, there is a need to identify modifiable risk factors associated with delirium to promote early diagnosis and implement evidence-based management strategies to enhance outcomes within this population. Copyright © 2024 Academy of Consultation-Liaison Psychiatry. Published by Elsevier Inc. All rights reserved.
520			_aMETHODS: This retrospective study included all adult patients who received LVADs at our institution between January 2016 and December 2020. We compared preimplantation characteristics between the two groups, with and without a diagnosis of delirium, and compared their outcomes, including 1-month, 6-month, and in-hospital mortality, as well as reintubation rate, length of stay, discharge disposition, and readmission rates.
520			_aOBJECTIVE: This study investigates the impact of a delirium diagnosis on outcomes after left ventricular assist device (LVAD) implantation.
520			_aRESULTS: In total, 361 patients (26.7% women and 75.8% African American) received durable LVADs. Ninety-four patients (26.1%) were diagnosed with delirium during the index admission. Preimplantation demographic characteristics, past medical and psychiatric conditions, Interagency Registry for Mechanically Assisted Circulatory Support Profile, and laboratory values did not differ between the two groups with and without a diagnosis of delirium; older age (59 vs 56; P = 0.03) was associated with delirium. Delirium diagnosis was associated with higher 1-month (P = 0.007), 6-month (P = 0.004), and in-hospital mortality (P < 0.001), unplanned reintubations (P < 0.001), and a lower likelihood of discharge home (P = 0.03). Total hospital and intensive care unit length of stay were higher in patients with a diagnosis of delirium, though these results were not statistically significant. Readmission to the hospital after index admission was quicker in patients with a diagnosis of delirium, but this result was not statistically significant.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
650			_zAutomated
651			_aMedStar Harbor Hospital
651			_aMedStar Heart & Vascular Institute
651			_aMedStar Washington Hospital Center
656			_aMedicine/Palliative Care
656			_aPalliative Care
657			_aJournal Article
700			_aGroninger, Hunter _bMWHC
700			_aMolina, Ezequiel _bMHVI
700			_aNoufi, Paul _bMHH
700			_aRao, Sriram D _bMHVI
790			_aNoufi P, Anderson KM, Crowell N, White Y, Molina E, Rao SD, Groninger H
856			_uhttps://dx.doi.org/10.1016/j.jaclp.2024.04.005 _zhttps://dx.doi.org/10.1016/j.jaclp.2024.04.005
942			_cART _dArticle
999			_c14424 _d14424