000			03510nam a22004457a 4500
008			240807s20242024 xxu||||| |||| 00| 0 eng d
022			_a1547-5271
024			_aS1547-5271(24)00355-2 [pii]
040			_aOvid MEDLINE(R)
099			_a38752906
245			_aTrends in safety of catheter-based electrophysiology procedures in the last 2 decades: A meta-analysis.
251			_aHeart Rhythm. 2024 Apr 16
252			_aHeart Rhythm. 2024 Apr 16
253			_aHeart rhythm
260			_c2024
260			_fFY2024
260			_p2024 Apr 16
265			_saheadofprint
265			_tPublisher
266			_d2024-08-07
266			_z2024/05/16 10:33
501			_aAvailable online through MWHC library: 2004 - present
520			_aBACKGROUND: Rapid technologic development and expansion of procedural expertise have led to widespread proliferation of catheter-based electrophysiology procedures. It is unclear whether these advances come at cost to patient safety.
520			_aCONCLUSION: Despite an increase in cardiac electrophysiology procedures, procedural safety has improved over time. Copyright © 2024 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.
520			_aMETHODS: A comprehensive search was performed to identify relevant data published before May 30, 2023. Studies were included if they met the following inclusion criteria: prospective trials or registries, including comprehensive complications data; and patients undergoing atrial fibrillation ablation, ventricular tachyarrhythmia ablation, leadless cardiac pacemaker implantation, and percutaneous left atrial appendage occlusion. Pooled incidences of procedure-related complications were individually assessed by random effects models to account for heterogeneity. Temporal trends in complications were investigated by clustering trials by publication year (2000-2018 vs 2019-2023).
520			_aOBJECTIVE: This meta-analysis aimed to assess complication rates after modern electrophysiology procedures during the lifetime of the procedures.
520			_aRESULTS: A total of 174 studies (43,914 patients) met criteria for analysis: 126 studies of atrial fibrillation ablation (n = 24,057), 25 studies of ventricular tachyarrhythmia ablation (n = 1781), 21 studies of leadless cardiac pacemaker (n = 8896), and 18 studies of left atrial appendage occlusion (n = 9180). The pooled incidences of serious procedure-related complications (3.49% [2000-2018] vs 3.05% [2019-2023]; P < .001), procedure-related stroke (0.46% vs 0.28%; P = .002), pericardial effusion requiring intervention (1.02% vs 0.83%; P = .037), and procedure-related death (0.15% vs 0.06%; P = .003) significantly decreased over time. However, there was no significant difference in the incidence of vascular complications over time (1.86% vs 1.88%; P = .888).
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
650			_zAutomated
651			_aMedStar Washington Hospital Center
656			_aCardiovascular Disease Fellowship
656			_aClinical Cardiac Electrophysiology Fellowship
657			_aJournal Article
700			_aBasyal, Binaya _bMWHC _cClinical Cardiac Electrophysiology Fellowship _dMBBS
700			_aOates, Connor _bMWHC _cCardiovascular Disease Fellowship _dMD
790			_aOates CP, Basyal B, Whang W, Reddy VY, Koruth JS
856			_uhttps://dx.doi.org/10.1016/j.hrthm.2024.03.043 _zhttps://dx.doi.org/10.1016/j.hrthm.2024.03.043
942			_cART _dArticle
999			_c14431 _d14431