000 | 02656nam a22004337a 4500 | ||
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008 | 240807s20242024 xxu||||| |||| 00| 0 eng d | ||
022 | _a2328-8957 | ||
024 | _aofae286 [pii] | ||
024 | _aPMC11167671 [pmc] | ||
040 | _aOvid MEDLINE(R) | ||
099 | _a38868314 | ||
245 | _aFungal Foe and Mechanical Hearts: A Retrospective Case Series on Candida auris Bloodstream Infection With Left Ventricular Assist Devices. | ||
251 | _aOpen Forum Infectious Diseases. 11(6):ofae286, 2024 Jun. | ||
252 | _aOpen forum infect. dis.. 11(6):ofae286, 2024 Jun. | ||
253 | _aOpen forum infectious diseases | ||
260 | _c2024 | ||
260 | _fFY2024 | ||
260 | _p2024 Jun | ||
265 | _sepublish | ||
265 | _tPubMed-not-MEDLINE | ||
266 | _d2024-08-07 | ||
266 | _z2024/06/13 04:30 | ||
520 | _aNo guidelines currently exist for the management of Candida auris bloodstream infection in patients with left ventricular assist devices (LVADs). We aim to share our management experience through this retrospective case series outlining 15 episodes of C auris candidemia identified in 7 patients over 18 months. The initial source of candidemia was central venous catheter in 5 patients, driveline exit site infection in 1 patient, and possible pump infection in 1 patient. All patients were initially treated with micafungin. Despite susceptibility to micafungin, 4 patients experienced recurrent C auris candidemia. All patients died within 1 year of their first episode of C auris candidemia. Source control is challenging in patients with LVADs, and strict infection prevention measures should be practiced. More studies are needed to evaluate the role of newer antifungal agents, use of combination antifungal regimens, and impact on morbidity in patients with LVADs. Copyright © The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. | ||
546 | _aEnglish | ||
650 | _zAutomated | ||
651 | _aMedStar Washington Hospital Center | ||
656 | _aDepartment of Internal Medicine/Infectious Disease | ||
656 | _aInternal Medicine Residency | ||
656 | _aPhysical Medicine and Rehabilitation | ||
657 | _aCase Reports | ||
657 | _aJournal Article | ||
700 |
_aDoshi, Saumil _bMWHC |
||
700 |
_aKerai, Ajay _bMWHC _cInternal Medicine Residency _dMD |
||
700 |
_aLaleker, Ashley _bMWHC |
||
790 | _aKerai A, Doshi S, Laleker A, Majumdar A | ||
856 |
_uhttps://dx.doi.org/10.1093/ofid/ofae286 _zhttps://dx.doi.org/10.1093/ofid/ofae286 |
||
858 |
_yKerai, Ajay _uhttps://orcid.org/0009-0002-3818-4012 _zhttps://orcid.org/0009-0002-3818-4012 |
||
942 |
_cART _dArticle |
||
999 |
_c14481 _d14481 |