000			03317nam a22006257a 4500
008			240807s20242024 xxu||||| |||| 00| 0 eng d
022			_a1774-024X
024			_aEIJ-D-23-01087 [pii]
024			_aPMC11200663 [pmc]
040			_aOvid MEDLINE(R)
099			_a38949240
245			_aCerebrovascular events after transcatheter aortic valve implantation. [Review]
251			_aEurointervention. 20(13):e793-e805, 2024 Jul 01.
252			_aEuroIntervention. 20(13):e793-e805, 2024 Jul 01.
253			_aEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
260			_c2024
260			_fFY2025
260			_p2024 Jul 01
265			_sepublish
265			_tMEDLINE
266			_d2024-08-07
266			_z2024/07/01 08:22
520			_aPeriprocedural stroke after transcatheter aortic valve implantation (TAVI) remains a significant issue, which is associated with high morbidity, and is increasingly important as intervention shifts to younger and lower-risk populations. Over the last decade of clinical experience with TAVI, the incidence of periprocedural stroke has stayed largely unchanged, although it is prone to underreporting due to variation in ascertainment methods. The aetiology of stroke in TAVI patients is multifactorial, and changing risk profiles, differing study populations, and frequent device iterations have made it difficult to discern consistent risk factors. The objective of this review is to analyse and clarify the contemporary published literature on the epidemiology and mechanisms of neurological events in TAVI patients and evaluate potential preventive measures. This summary aims to improve patient risk assessment and refine case selection for cerebral embolic protection devices, while also providing a foundation for designing future trials focused on stroke prevention.
546			_aEnglish
650			_a*Aortic Valve Stenosis
650			_a*Stroke
650			_a*Transcatheter Aortic Valve Replacement
650			_aAortic Valve Stenosis/su [Surgery]
650			_aAortic Valve/su [Surgery]
650			_aEmbolic Protection Devices
650			_aHumans
650			_aIncidence
650			_aRisk Assessment
650			_aRisk Factors
650			_aStroke/et [Etiology]
650			_aStroke/pc [Prevention & Control]
650			_aTranscatheter Aortic Valve Replacement/ae [Adverse Effects]
650			_aTranscatheter Aortic Valve Replacement/is [Instrumentation]
650			_aTreatment Outcome
650			_zAutomated
651			_aMedStar Heart & Vascular Institute
651			_aMedStar Washington Hospital Center
656			_aAdvanced Cardiac Catheterization Research Fellowship
657			_aJournal Article
657			_aReview
700			_aBen-Dor, Itsik _bMHVI
700			_aMerdler, Ilan _bMHVI
700			_aReddy, Pavan _bMWHC _cAdvanced Cardiac Catheterization Research Fellowship _dMD
700			_aRogers, Toby _bMHVI
700			_aSatler, Lowell F _bMHVI
700			_aWaksman, Ron _bMHVI
790			_aReddy P, Merdler I, Ben-Dor I, Satler LF, Rogers T, Waksman R
856			_uhttps://dx.doi.org/10.4244/EIJ-D-23-01087 _zhttps://dx.doi.org/10.4244/EIJ-D-23-01087
942			_cART _dArticle
999			_c14559 _d14559