000			04156nam a22006737a 4500
008			240807s20242024 xxu||||| |||| 00| 0 eng d
022			_a0167-5273
024			_aS0167-5273(24)00733-2 [pii]
040			_aOvid MEDLINE(R)
099			_a38697401
245			_aImpact of anemia on outcomes and resource utilization in patients with myocardial infarction: A national database analysis.
251			_aInternational Journal of Cardiology. 408:132111, 2024 Aug 01.
252			_aInt J Cardiol. 408:132111, 2024 Aug 01.
253			_aInternational journal of cardiology
260			_c2024
260			_fFY2024
260			_p2024 Aug 01
265			_sppublish
265			_tMEDLINE
266			_d2024-08-07
266			_z2024/05/02 19:27
520			_aBACKGROUND: Although anemia is common in patients with myocardial infarction (MI), management remains controversial. We quantified the association of anemia with in-hospital outcomes and resource utilization in patients admitted with MI using a large national database.
520			_aCONCLUSION: In MI patients, anemia was associated with higher in-hospital mortality, adverse events, total cost, and length of stay. Transfusion was associated with increased mortality, and its role in MI requires further research. Copyright © 2023. Published by Elsevier B.V.
520			_aMETHODS: All hospitalizations with a primary diagnosis code for acute MI in the National Inpatient Sample (NIS) between 2014 and 2018 were identified. Among these hospitalizations, patients with anemia were identified using a secondary diagnosis code. Data on demographic and clinical variables were collected. Outcomes of interest included in-hospital adverse events, length of stay (LOS), and total cost. Multivariable logistic regression and generalized linear models were used to evaluate the relationship between anemia and outcomes.
520			_aRESULTS: Among 1,113,181 MI hospitalizations, 254,816 (22.8%) included concomitant anemia. Anemic patients were older and more likely to be women. After adjustment for demographics and comorbidities, anemia was associated with higher mortality (7.1 vs. 4.3%; odds ratio 1.09; 95% confidence interval [CI] 1.07-1.12, p < 0.001). Anemia was also associated with a mean of 2.71 days longer LOS (average marginal effects [AME] 2.71; 95% CI 2.68-2.73, p < 0.05), and _ 9703 mean higher total costs (AME _9703, 95% CI _9577- _9829, p < 0.05). Anemic patients who received blood transfusions had higher mortality as compared with those who did not (8.2% vs. 7.0, p < 0.001).
546			_aEnglish
650			_a*Anemia
650			_a*Databases, Factual
650			_a*Myocardial Infarction
650			_aAged
650			_aAged, 80 and over
650			_aAnemia/ec [Economics]
650			_aAnemia/ep [Epidemiology]
650			_aAnemia/th [Therapy]
650			_aFemale
650			_aHealth Resources/ec [Economics]
650			_aHealth Resources/sn [Statistics & Numerical Data]
650			_aHospital Mortality/td [Trends]
650			_aHospitalization/ec [Economics]
650			_aHospitalization/sn [Statistics & Numerical Data]
650			_aHumans
650			_aLength of Stay/sn [Statistics & Numerical Data]
650			_aMale
650			_aMiddle Aged
650			_aMyocardial Infarction/co [Complications]
650			_aMyocardial Infarction/ec [Economics]
650			_aMyocardial Infarction/ep [Epidemiology]
650			_aMyocardial Infarction/th [Therapy]
650			_aRetrospective Studies
650			_aUnited States/ep [Epidemiology]
650			_zAutomated
651			_aMedStar Washington Hospital Center
656			_aAdvanced Cardiac Catheterization Research Fellowship
657			_aJournal Article
700			_aAbusnina, Waiel _bMWHC _cAdvanced Cardiac Catheterization Research Fellowship _dMBBCh
790			_aJhand AS, Abusnina W, Tak HJ, Ahmed A, Ismayl M, Altin SE, Sherwood MW, Alexander JH, Rao SV, Abbott JD, Carson JL, Goldsweig AM
856			_uhttps://dx.doi.org/10.1016/j.ijcard.2024.132111 _zhttps://dx.doi.org/10.1016/j.ijcard.2024.132111
942			_cART _dArticle
999			_c14601 _d14601