000 02638nam a22004217a 4500
008 241030s20242024 xxu||||| |||| 00| 0 eng d
022 _a1061-5377
024 _a00045415-990000000-00305 [pii]
040 _aOvid MEDLINE(R)
099 _a39078143
245 _aPreparing the Heart for a New Baby: Management of Pregnancy in Heart Transplant Recipients.
251 _aCardiology in Review. 2024 Jul 30
252 _aCardiol Rev. 2024 Jul 30
253 _aCardiology in review
260 _c2024
260 _fFY2025
260 _p2024 Jul 30
265 _saheadofprint
265 _tPublisher
266 _d2024-10-30
266 _z2024/07/30 09:03
501 _aAvailable online from MWHC library: 2001 - present
520 _aHeart transplant (HT) recipients are more frequently reaching childbearing age given improvement in median survival and outcomes after HT. Although most pregnancies in HT recipients have favorable outcomes, poor fetal outcomes and maternal complications such as hypertensive disorders of pregnancy are more common in HT recipients than in the general population. In this review, we summarize the current evidence to guide the management of pregnancy in HT recipients. Preconception counseling, focused on risk stratification and optimal timing of conception, is the first important step to optimize pregnancy outcomes. During pregnancy and in the postpartum period, frequent monitoring of graft function and immunosuppressive levels is recommended. Calcineurin inhibitors and corticosteroids should be the mainstay of treatment for both prevention and treatment of graft rejection. Delivery planning should follow usual obstetric indications, preferably with vaginal delivery at term using regional anesthesia. A multidisciplinary care team should be involved in management through all stages of pregnancy to ensure success. Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
546 _aEnglish
650 _zAutomated
650 _aIN PROCESS -- NOT YET INDEXED
651 _aMedStar Heart & Vascular Institute
651 _aMedStar Washington Hospital Center
656 _aCardiovascular Disease Fellowship
657 _aJournal Article
700 _aGupta, Richa
_bMHVI
700 _aHussien, Merna
_bMHVI
_cCardiovascular Disease Fellowship
_dMD
700 _aLam, Phillip H
_bMHVI
700 _aLorente-Ros, Marta
_bMHVI
790 _aHussien M, Lorente-Ros M, Lam PH, Frishman WH, Aronow WS, Gupta R
856 _uhttps://dx.doi.org/10.1097/CRD.0000000000000758
_zhttps://dx.doi.org/10.1097/CRD.0000000000000758
942 _cART
_dArticle
999 _c14708
_d14708