000			03675nam a22005537a 4500
008			241030s20242024 xxu||||| |||| 00| 0 eng d
022			_a1058-2916
024			_a00002480-990000000-00532 [pii]
040			_aOvid MEDLINE(R)
099			_a39074441
245			_aImpact of Cardiac Resynchronization Therapy on Ventricular Arrhythmias and Survival After Durable Left Ventricular Assist Device Implantation.
251			_aASAIO Journal. 2024 Jul 29
252			_aASAIO J. 2024 Jul 29
253			_aASAIO journal (American Society for Artificial Internal Organs : 1992)
260			_c2024
260			_fFY2025
260			_p2024 Jul 29
265			_saheadofprint
265			_tPublisher
266			_d2024-10-30
266			_z2024/07/29 18:02
501			_aAvailable online from MWHC library: 2000 - present, Available in print through MWHC library: 1999 - 2003
520			_aThe impact of cardiac resynchronization therapy (CRT) in patients receiving durable left ventricular assist device (LVAD) implantation remains unclear and there is no consensus regarding postoperative management. We sought to determine the impact of postoperative management of CRT on clinical outcomes following LVAD implantation. A total of 789 patients underwent LVAD implantation at our institution from 2007 to 2022 including 195 patients (24.7%) with preoperative CRT. Patients with preoperative CRT were significantly older and more frequently received an LVAD as destination therapy compared to patients without preoperative CRT. After LVAD implantation, 85 patients had CRT programmed "off" and 74 patients had CRT programmed "on." The risk of mortality was significantly increased amongst patients with preoperative CRT that was turned "on" following LVAD implantation compared to patients with preoperative CRT turned "off" following implant (subdistribution hazard ratio [sdHR] = 1.54; 1.06-2.37 95% confidence interval [CI]; p = 0.036). There was no significant difference between incidence of ventricular arrhythmias in patients with and without postoperative CRT "on" (35.1% vs. 48.2%; p = 0.095). Additional clinical trials are warranted to determine the best CRT programming strategy following LVAD implantation. Copyright © ASAIO 2024.
546			_aEnglish
650			_zAutomated
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Heart & Vascular Institute
651			_aMedStar Washington Hospital Center
656			_aCardiovascular Disease Fellowship
656			_aClinical Cardiac Electrophysiology Fellowship
656			_aInternal Medicine Residency
656			_aMedStar Georgetown University Hospital/MedStar Washington Hospital Center
657			_aJournal Article
700			_aBasyal, Binaya _bMWHC _cClinical Cardiac Electrophysiology Fellowship _dMBBS
700			_aBigham, Grace _bMGUH _cInternal Medicine Residency _dMD
700			_aHadadi, Cyrus A _bMHVI
700			_aLam, Phillip H _bMHVI
700			_aLawrence, Luke _bMGUH _cInternal Medicine Residency _dMD
700			_aMeda, Namratha S _bMHVI
700			_aNajjar, Samer S _bMHVI
700			_aOates, Connor _bMWHC _cCardiovascular Disease Fellowship _dMD
700			_aRao, Sriram _bMHVI
700			_aShah, Manish H _bMHVI
700			_aSheikh, Farooq H _bMHVI
790			_aOates CP, Lawrence LL, Bigham GE, Meda NS, Basyal B, Rao SD, Hadadi CA, Najjar SS, Shah MH, Sheikh FH, Lam PH
856			_uhttps://dx.doi.org/10.1097/MAT.0000000000002279 _zhttps://dx.doi.org/10.1097/MAT.0000000000002279
858			_yOates, Connor P _uhttps://orcid.org/0000-0003-2250-4608 _zhttps://orcid.org/0000-0003-2250-4608
942			_cART _dArticle
999			_c14709 _d14709