000 02187nam a22003977a 4500
008 170512s20172017 xxu||||| |||| 00| 0 eng d
022 _a1093-5266
040 _aOvid MEDLINE(R)
099 _a28488469
245 _aExtramedullary Hematopoiesis Presenting as Bilateral Glomus Tympanicum-First Case Report in a Pediatric Patient and With Bilateral Presentation.
251 _aPediatric & Developmental Pathology. 21(3):332-334, 2018 May-Jun.
252 _aPediatr Dev Pathol. 21(3):332-334, 2018 May-Jun.
253 _aPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
260 _c2018
260 _fFY2018
266 _d2017-05-24
269 _fFY2017
520 _aTo the best of our knowledge, this is the first case report of middle ear extramedullary hematopoiesis (EMH) in a pediatric patient as well as the first bilateral presentation reported in both children and adults. We report a 13-year-old African-American female with sickle cell disease who developed bilateral hearing loss, with magnetic resonance imaging findings consistent with bilateral glomus tympanicum (GT). Upon excisional biopsy, however, EMH was diagnosed histologically. Besides its novelty, this case highlights the importance of considering EMH in the differential diagnosis of GT including cases with bilateral presentation that may be otherwise highly suggestive of the familial form of GT.
546 _aEnglish
650 _a*Ear Neoplasms/di [Diagnosis]
650 _a*Ear, Middle/pa [Pathology]
650 _a*Glomus Tympanicum Tumor/di [Diagnosis]
650 _a*Hematopoiesis, Extramedullary
650 _aAdolescent
650 _aEar Neoplasms/pa [Pathology]
650 _aFemale
650 _aGlomus Tympanicum Tumor/pa [Pathology]
650 _aHumans
651 _aMedStar Washington Hospital Center
656 _aPathology
657 _aJournal Article
700 _aChen, Leonard N
790 _aChen LN, Espinel A, Luca DC, Reilly B
856 _uhttps://dx.doi.org/10.1177/1093526617704267
_zhttps://dx.doi.org/10.1177/1093526617704267
942 _cART
_dArticle
999 _c2225
_d2225