000 02119nam a22004817a 4500
008 170707s20162016 xxu||||| |||| 00| 0 eng d
022 _a0021-972X
040 _aOvid MEDLINE(R)
099 _a26900641
245 _aLong-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.
251 _aJournal of Clinical Endocrinology & Metabolism. 101(4):1754-61, 2016 Apr
252 _aJ Clin Endocrinol Metab. 101(4):1754-61, 2016 Apr
253 _aThe Journal of clinical endocrinology and metabolism
260 _c2016
260 _fFY2016
266 _d2017-07-07
501 _aAvailable online through MWHC library: 1999- June 2013, Available in print through MWHC library: 1999 - 2006
520 _aParticipants from DPP/DPPOS were assigned to placebo (n=1082) or metformin (n=1073) for 3.2 years, followed by metformin in the metformin group for 9 years. Metformin use was associated with increased risk of vitamin B12 deficiency.
546 _aEnglish
650 _a*Anemia/ci [Chemically Induced]
650 _a*Diabetes Mellitus, Type 2/pc [Prevention & Control]
650 _a*Hypoglycemic Agents/ae [Adverse Effects]
650 _a*Metformin/ae [Adverse Effects]
650 _a*Vitamin B 12 Deficiency/ci [Chemically Induced]
650 _aAdult
650 _aAged
650 _aFemale
650 _aHomocysteine/bl [Blood]
650 _aHumans
650 _aHypoglycemic Agents/tu [Therapeutic Use]
650 _aMale
650 _aMetformin/tu [Therapeutic Use]
650 _aMiddle Aged
650 _aVitamin B 12/bl [Blood]
651 _aMedStar Health Research Institute
657 _aJournal Article
657 _aMulticenter Study
657 _aRandomized Controlled Trial
700 _aAroda, Vanita R
790 _aAroda VR, Bray GA, Crandall JP, Diabetes Prevention Program Research Group, Edelstein SL, Goldberg RB, Knowler WC, Marcovina SM, Orchard TJ, Schade DS, Temprosa MG, White NH
856 _uhttps://dx.doi.org/10.1210/jc.2015-3754
_zhttps://dx.doi.org/10.1210/jc.2015-3754
942 _cART
_dArticle
999 _c2464
_d2464