000			03431nam a22006977a 4500
008			170512s20172017 xxu||||| |||| 00| 0 eng d
022			_a0890-5096
040			_aOvid MEDLINE(R)
099			_a28479472
245			_aImplications of Clostridium septicum in vascular surgery: a case report and outcomes literature review.
251			_aAnnals of Vascular Surgery. 43:314.e5-314.e11, 2017 Aug
252			_aAnn Vasc Surg. 43:314.e5-314.e11, 2017 Aug
253			_aAnnals of vascular surgery
260			_c2017
260			_fFY2017
266			_d2017-05-24
501			_aAvailable online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007
520			_aClostridium septicum is a rare organism, accounting for approximately 1.3% of clostridial infections and is associated with synchronous colonic malignancy. This case report describes a patient successfully treated for a mycotic aortic aneurysm secondary to C. septicum bacteremia. Subsequent evaluation confirmed a colonic malignancy, prompting early intervention. A systematic literature review revealing a rate of gastrointestinal malignancy in this patient population is 71%, hematologic malignancy is 3.9%, with the remaining cohort of patients having an unknown source. Infectious involvement of the aorta and associated vascular structures portends a poor prognosis with a 57% mortality rate. Our case and updated review demonstrates the implications of C. septicum vascular seeding and subsequent treatment outcomes.
520			_aCopyright (C) 2017 Elsevier Inc. All rights reserved.
546			_aEnglish
650			_a*Adenocarcinoma/mi [Microbiology]
650			_a*Aneurysm, Infected/su [Surgery]
650			_a*Aortic Aneurysm, Abdominal/su [Surgery]
650			_a*Blood Vessel Prosthesis Implantation
650			_a*Clostridium Infections/su [Surgery]
650			_a*Clostridium septicum/ip [Isolation & Purification]
650			_a*Colonic Neoplasms/mi [Microbiology]
650			_aAdenocarcinoma/dg [Diagnostic Imaging]
650			_aAdenocarcinoma/su [Surgery]
650			_aAdult
650			_aAged
650			_aAged, 80 and over
650			_aAneurysm, Infected/dg [Diagnostic Imaging]
650			_aAneurysm, Infected/mi [Microbiology]
650			_aAnti-Bacterial Agents/tu [Therapeutic Use]
650			_aAortic Aneurysm, Abdominal/dg [Diagnostic Imaging]
650			_aAortic Aneurysm, Abdominal/mi [Microbiology]
650			_aAortography/mt [Methods]
650			_aBiopsy
650			_aClostridium Infections/dg [Diagnostic Imaging]
650			_aClostridium Infections/mi [Microbiology]
650			_aColectomy
650			_aColonic Neoplasms/dg [Diagnostic Imaging]
650			_aColonic Neoplasms/su [Surgery]
650			_aColonoscopy
650			_aComputed Tomography Angiography
650			_aEarly Detection of Cancer/mt [Methods]
650			_aFemale
650			_aHumans
650			_aMale
650			_aMiddle Aged
650			_aTreatment Outcome
651			_aMedStar Washington Hospital Center
656			_aSurgery
657			_aJournal Article
700			_aAlimi, Yewande
700			_aSosin, Michael
790			_aAlimi Y, Borsinger TM, Espinel CF, Garrett JR, Salameh JR, Sosin M
856			_uhttps://dx.doi.org/10.1016/j.avsg.2017.03.178 _zhttps://dx.doi.org/10.1016/j.avsg.2017.03.178
942			_cART _dArticle
999			_c2948 _d2948