| 000 | 04854nam a22008777a 4500 | ||
|---|---|---|---|
| 008 | 181010s20192019 xxu||||| |||| 00| 0 eng d | ||
| 022 | _a1522-1946 | ||
| 040 | _aOvid MEDLINE(R) | ||
| 099 | _a30280469 | ||
| 245 | _aRole of contractile reserve as a predictor of mortality in low-flow, low-gradient severe aortic stenosis following transcatheter aortic valve replacement. | ||
| 251 | _aCatheterization & Cardiovascular Interventions. 93(4):707-712, 2019 03 01. | ||
| 252 | _aCatheter Cardiovasc Interv. 93(4):707-712, 2019 03 01. | ||
| 252 | _zCatheter Cardiovasc Interv. 2018 Oct 02 | ||
| 253 | _aCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions | ||
| 260 | _c2019 | ||
| 260 | _fFY2019 | ||
| 265 | _saheadofprint | ||
| 265 | _sppublish | ||
| 266 | _d2018-10-10 | ||
| 268 | _aCatheterization & Cardiovascular Interventions. 2018 Oct 02 | ||
| 501 | _aAvailable online from MWHC library: 1996 - present, Available in print through MWHC library: 1996 - 2006 | ||
| 520 | _aBACKGROUND: Patients with severe AS, left ventricular dysfunction, and low transaortic gradient are at high risk for mortality during surgical aortic valve replacement (SAVR). Furthermore, patients without CR have been shown to have perioperative mortality comparable to that of patients treated medically for severe AS. | ||
| 520 | _aCONCLUSION: In patients with low-flow, low-gradient severe AS undergoing TAVR, the presence or absence of CR does not predict all-cause mortality at 30 days or 1 year. | ||
| 520 | _aCopyright (c) 2018 Wiley Periodicals, Inc. | ||
| 520 | _aMETHODS: We retrospectively analyzed patients who underwent TAVR with a diagnosis of low-gradient severe AS (mean transvalvular aortic gradient < 40 mmHg, LVEF < 50%, and AVA <= 1.0 cm<sup>2</sup> or AVAi <= 0.6 cm<sup>2</sup> ) and who had a pre-TAVR dobutamine stress echocardiogram (DSE). Patients were stratified by the presence or absence of CR, defined as an increase in stroke volume >= 20% during DSE. | ||
| 520 | _aOBJECTIVES: The aim of this study was to determine the prognostic value of contractile reserve (CR) at baseline in patients with low-flow, low-gradient severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR). | ||
| 520 | _aRESULTS: From 2008 to 2016, 61 patients with low-gradient severe AS underwent TAVR and had pre-TAVR DSE. CR was present in 31 patients (51%) and absent in 30 (49%). There was no significant difference between the two groups in baseline demographics, medical history, access site, or types of valves. All-cause mortality was similar in both groups at 30 days (13% with CR vs 10% without CR, P = 1.00) and 1 year (29% with CR vs 33% without CR, HR 1.20, 95% CI 0.49-2.96, P = 0.69). | ||
| 546 | _aEnglish | ||
| 650 | _a*Aortic Valve Stenosis/su [Surgery] | ||
| 650 | _a*Aortic Valve/su [Surgery] | ||
| 650 | _a*Hemodynamics | ||
| 650 | _a*Myocardial Contraction | ||
| 650 | _a*Transcatheter Aortic Valve Replacement/mo [Mortality] | ||
| 650 | _a*Ventricular Dysfunction, Left/pp [Physiopathology] | ||
| 650 | _a*Ventricular Function, Left | ||
| 650 | _aAged | ||
| 650 | _aAged, 80 and over | ||
| 650 | _aAortic Valve Stenosis/dg [Diagnostic Imaging] | ||
| 650 | _aAortic Valve Stenosis/mo [Mortality] | ||
| 650 | _aAortic Valve Stenosis/pp [Physiopathology] | ||
| 650 | _aAortic Valve/dg [Diagnostic Imaging] | ||
| 650 | _aAortic Valve/pp [Physiopathology] | ||
| 650 | _aDatabases, Factual | ||
| 650 | _aFemale | ||
| 650 | _aHumans | ||
| 650 | _aMale | ||
| 650 | _aRecovery of Function | ||
| 650 | _aRetrospective Studies | ||
| 650 | _aRisk Assessment | ||
| 650 | _aRisk Factors | ||
| 650 | _aSeverity of Illness Index | ||
| 650 | _aStroke Volume | ||
| 650 | _aTime Factors | ||
| 650 | _aTranscatheter Aortic Valve Replacement/ae [Adverse Effects] | ||
| 650 | _aTreatment Outcome | ||
| 650 | _aVentricular Dysfunction, Left/dg [Diagnostic Imaging] | ||
| 650 | _aVentricular Dysfunction, Left/mo [Mortality] | ||
| 651 | _aMedStar Heart & Vascular Institute | ||
| 657 | _aJournal Article | ||
| 700 | _aAsch, Federico M | ||
| 700 | _aBen-Dor, Itsik | ||
| 700 | _aBuchanan, Kyle | ||
| 700 | _aKoifman, Edward | ||
| 700 | _aOkubagzi, Petros | ||
| 700 | _aPichard, Augusto D | ||
| 700 | _aRogers, Toby | ||
| 700 | _aSatler, Lowell F | ||
| 700 | _aShults, Christian | ||
| 700 | _aSteinvil, Arie | ||
| 700 | _aTorguson, Rebecca | ||
| 700 | _aWaksman, Ron | ||
| 700 | _aXu, Linzhi | ||
| 790 | _aAsch FM, Ben-Dor I, Buchanan KD, Koifman E, Okubagzi PG, Pichard AD, Rogers T, Satler LF, Shults C, Steinvil A, Torguson R, Waksman R, Xu L | ||
| 856 |
_uhttps://dx.doi.org/10.1002/ccd.27914 _zhttps://dx.doi.org/10.1002/ccd.27914 |
||
| 942 |
_cART _dArticle |
||
| 999 |
_c3787 _d3787 |
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