000 02866nam a22004697a 4500
008 181214s20182018 xxu||||| |||| 00| 0 eng d
022 _a0960-7404
024 _a10.1016/j.suronc.2018.08.005 [doi]
024 _aS0960-7404(18)30055-0 [pii]
040 _aOvid MEDLINE(R)
099 _a30449489
245 _aSclerosing encapsulating peritonitis as a potential complication of cytoreductive surgery and HIPEC: Clinical features and results of treatment in 4 patients.
251 _aSurgical Oncology. 27(4):657-662, 2018 Dec.
252 _aSurg Oncol. 27(4):657-662, 2018 Dec.
253 _aSurgical oncology
260 _c2018
260 _fFY2019
265 _sppublish
266 _d2018-12-14
520 _aCopyright (c) 2018 Elsevier Ltd. All rights reserved.
520 _aSclerosing encapsulating peritonitis (SEP) is a rare entity characterized by encapsulation of the small bowel and/or the colon by a fibrous tissue that forms a shell. Intraperitoneal chemotherapy (IPC) has been reported to be a potential causative factor of secondary SEP. However, few studies have reported on secondary SEP related to cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Here, we review results from four clinical cases of SEP associated with CRS and HIPEC. In all four patients, additional surgery was necessary to alleviate recurrent episodes of small bowel obstruction. These obstructions can occur as early as several weeks after CRS plus HIPEC or as late as 3 years after treatment. Of utmost importance is the prevention of fistulization which can result in enteric contamination of the peritoneal space. To date, no solution to SEP has been identified except additional surgery but it is evident that these reoperative experiences are difficult for both surgeon and patient. The etiopathogenesis of SEP in this setting remains unknown but it is clear that it is related to chronic inflammation of the peritoneum. Large studies are needed to identify the incidence and potential common causes of SEP after CRS and HIPEC.
546 _aEnglish
650 _a*Cytoreduction Surgical Procedures/ae [Adverse Effects]
650 _a*Peritoneal Neoplasms/co [Complications]
650 _a*Peritoneal Neoplasms/su [Surgery]
650 _a*Peritonitis/et [Etiology]
650 _a*Peritonitis/pa [Pathology]
650 _aAdult
650 _aAged
650 _aFemale
650 _aHumans
650 _aMale
650 _aMiddle Aged
650 _aPeritoneal Neoplasms/sc [Secondary]
650 _aPrognosis
651 _aWashington Cancer Institute
657 _aJournal Article
700 _aSugarbaker, Paul H
790 _aLiberale G, Sugarbaker PH
856 _uhttps://dx.doi.org/10.1016/j.suronc.2018.08.005
_zhttps://dx.doi.org/10.1016/j.suronc.2018.08.005
942 _cART
_dArticle
999 _c3950
_d3950