000 02270nam a22003617a 4500
008 190314s20152015 xxu||||| |||| 00| 0 eng d
022 _a2000-9666
024 _a10.3402/jchimp.v5.27825 [doi]
024 _a27825 [pii]
024 _aPMC4558280 [pmc]
040 _aOvid MEDLINE(R)
099 _a26333854
245 _aNon-ketotic hyperglycemia unmasks hemichorea.
251 _aJournal of Community Hospital Internal Medicine Perspectives. 5(4):27825, 2015.
252 _aJ Community Hosp Intern Med Perspect. 5(4):27825, 2015.
253 _aJournal of community hospital internal medicine perspectives
260 _c2015
260 _fFY2015
265 _sepublish
266 _d2019-03-14
520 _aBACKGROUND: Chorea can be caused by a variety of diseases, including neurodegenerative disorders, vascular events, toxic-metabolic states, and immunologic and infectious diseases. We describe a patient who presented with hemichorea as the initial manifestation of Diabetes Mellitus (DM) and responded partially to the glycemic control.
520 _aCASE REPORT: A 63-year-old, healthy Hispanic man with no prior history of medical illness presented with subacute onset, gradually progressive hemichorea of 6 weeks' duration. On evaluation, he was found to have non-ketotic hyperglycemia with high serum glucose (328 mg/dL), elevated hemoglobin A1C (9.9%), and absent ketones. Magnetic Resonance Imaging of the brain demonstrated hyper intense signals in bilateral basal ganglia on T1W images. He was diagnosed to have DM. Despite optimal glycemic control with insulin, the patient continued to have hemichorea at 3 months follow-up and required haloperidol for control of the involuntary movements.
520 _aSIGNIFICANCE: Involuntary movements, particularly hemichorea, can be a manifestation and rarely be a presenting sign of DM.
546 _aEnglish
650 _aPubMed-not-MEDLINE -- Not indexed
651 _aMedStar Washington Hospital Center
656 _aMedicine/Internal Medicine
657 _aCase Reports
700 _aBhoite, Girja Ramesh
790 _aBhoite G, Danve A, Kulkarni S
856 _uhttps://dx.doi.org/10.3402/jchimp.v5.27825
_zhttps://dx.doi.org/10.3402/jchimp.v5.27825
942 _cART
_dArticle
999 _c4132
_d4132