000			04676nam a22006977a 4500
008			191014s20192019 xxu||||| |||| 00| 0 eng d
022			_a1878-0938
024			_a10.1016/j.carrev.2019.05.027 [doi]
024			_aS1553-8389(19)30327-6 [pii]
040			_aOvid MEDLINE(R)
099			_a31208837
245			_aThe Impact of Blood Pressure Variability on Coronary Arterial Lumen Dimensions as Assessed by Optical Coherence Tomography in Patients with ST-Elevation Myocardial Infarction.
251			_aCardiovascular Revascularization Medicine. 20(9):768-774, 2019 Sep.
252			_aCardiovasc Revasc Med. 20(9):768-774, 2019 Sep.
252			_zCardiovasc Revasc Med. 20(9):768-774, 2019 Sep.
253			_aCardiovascular revascularization medicine : including molecular interventions
260			_c2019
260			_fFY2020
265			_sppublish
266			_d2019-10-14
268			_aCardiovascular Revascularization Medicine. 20(9):768-774, 2019 Sep.
520			_aBACKGROUND: Patients with ST-elevation Myocardial Infarction treated by primary percutaneous coronary intervention (PPCI) experience drastic hemodynamic systemic changes (i.e., blood pressure) during the different phases of the procedure. Optical coherence tomography is often used to unveil the underlying cause of STEMI (pre-PCI) and to optimize stent implantation (post-PCI). The impact of blood pressure variability on coronary lumen remains uncertain. This study aimed to investigate the relationship between blood pressure variability, before and after PCI, and coronary arterial lumen dimensions of the infarct-related artery.
520			_aCONCLUSION: Despite significant hemodynamic variability, the difference in lumen cross-sectional area, between pre- and post-coronary artery stenting was minimal. This study supports the use of OCT lumen areas to inform clinical decisions during PPCI. Copyright (c) 2019 Elsevier Inc. All rights reserved.
520			_aMETHODS: We measured systolic, diastolic and mean arterial blood pressure (SBP, DBP, and MAP; respectively) at pre- and post-PCI. Frequency-domain optical coherence tomography (FD-OCT) imaging was performed at the same time points. Offline quantitative image analyses were performed to assess the average and minimum lumen area (LA). DELTA blood pressure (after and before the PCI) was then calculated.
520			_aRESULTS: A total of 14 ST-segment elevation myocardial infarction (STEMI) patients were included. 84.2% of enrolled patients were male with a mean age of (58+/-10.7years). Roughly two-thirds (57.8%) had hypertension. The mean SBP was (112.6mmHg+/-16.1) and (117.2mmHg+/-20.9), pre- and post-stenting, respectively; the range of the observed SBP differences (between pre- and post-PCI) went from -25 to +23mmHg. Pre- and post-stenting mean average LA were (7.1+/-2.5mm2 and 6.8+/-2.3mm2; respectively). There were poor correlations between DELTASBP and DELTA mean minimum LA. A similar pattern was observed with DELTADBP and DELTAMAP.
546			_aEnglish
650			_a*Arterial Pressure
650			_a*Coronary Vessels/dg [Diagnostic Imaging]
650			_a*Coronary Vessels/pp [Physiopathology]
650			_a*Hypertension/pp [Physiopathology]
650			_a*ST Elevation Myocardial Infarction/dg [Diagnostic Imaging]
650			_a*ST Elevation Myocardial Infarction/pp [Physiopathology]
650			_a*Tomography, Optical Coherence
650			_aAged
650			_aFemale
650			_aHumans
650			_aHypertension/co [Complications]
650			_aHypertension/di [Diagnosis]
650			_aMale
650			_aMiddle Aged
650			_aPercutaneous Coronary Intervention/is [Instrumentation]
650			_aPredictive Value of Tests
650			_aRisk Factors
650			_aST Elevation Myocardial Infarction/co [Complications]
650			_aST Elevation Myocardial Infarction/th [Therapy]
650			_aStents
650			_aTime Factors
650			_aTreatment Outcome
651			_aMedStar Heart & Vascular Institute
656			_aMedicine/Internal Medicine
657			_aJournal Article
700			_aGarcia-Garcia, Hector M
700			_aHideo-Kajita, Alexandre
700			_aKuku, Kayode
700			_aOzaki, Yuichi
700			_aSoud, Mohamad
700			_aTariq, Muhammad Ali
790			_aBanning AP, Benenati S, Channon KM, De Maria GL, Dijkstra J, Garcia-Garcia HM, Hideo-Kajita A, Kuku K, Oxford Acute Myocardial Infarction (OxAMI) Study investigators, Ozaki Y, Soud M, Tariq MA
856			_uhttps://dx.doi.org/10.1016/j.carrev.2019.05.027 _zhttps://dx.doi.org/10.1016/j.carrev.2019.05.027
942			_cART _dArticle
999			_c4681 _d4681