000			02102nam a22003377a 4500
008			210218s20202020 xxu||||| |||| 00| 0 eng d
022			_a1998-4138
024			_a10.4103/jcrt.JCRT_12_19 [doi]
024			_a276928 [pii]
040			_aOvid MEDLINE(R)
099			_a33533734
245			_aGastric cancer in Jammu and Kashmir, India: A review of genetic perspectives. [Review]
251			_aJournal of Cancer Research & Therapeutics. 2020 Jan 27
252			_aJ Cancer Res Ther. 2020 Jan 27
253			_aJournal of cancer research and therapeutics
260			_c2020
260			_fFY2021
265			_saheadofprint
266			_d2021-02-18
520			_aGastric Carcinoma (GC) is one of the most common malignancies, which accounts for 6.8% of total cancer population worldwide. In India, the northeastern region has the highest gastric cancer incidence, and the Kashmir Valley has a very high incidence of gastric cancer as compared to other parts of Northern India. It exceeds 40% of total cancers with an incidence rate of 3-6-fold higher than other metro cities of India. Gastric cancer is a heterogeneous disease where most of the cases are sporadic, and <15% are due to obvious familial clustering. The heterogeneous nature of the disease can be associated with differences in genetic makeup of an individual. A better understanding of genetic predisposition toward GC will be helpful in promoting personalized medicine. The aim of this review is to analyze the development and progression of GC and to explore the genetic perspectives of the disease with special emphasis on Jammu and Kashmir, India.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Washington Hospital Center
656			_aSurgery/Thoracic Surgery
657			_aJournal Article
657			_aReview
700			_aGaur Khaitan, Puja
790			_aAbrol D, Kaul S, Khaitan PG, Kumar R, Pandita TK, Rafiq A, Shah R, Sharma S, Suri J
856			_uhttps://dx.doi.org/10.4103/jcrt.JCRT_12_19 _zhttps://dx.doi.org/10.4103/jcrt.JCRT_12_19
942			_cART _dArticle
999			_c6149 _d6149