000			02147nam a22003257a 4500
008			210607s20212021 xxu||||| |||| 00| 0 eng d
022			_a1757-790X
024			_a10.1136/bcr-2020-240619 [doi]
024			_a14/4/e240619 [pii]
024			_aPMC8048014 [pmc]
040			_aOvid MEDLINE(R)
099			_a33846184
245			_aUse of hyperbaric oxygenation as an adjunctive treatment for severe pernicious anaemia in a bloodless medicine patient.
251			_aBMJ Case Reports. 14(4), 2021 Apr 12.
252			_aBMJ Case Rep. 14(4), 2021 Apr 12.
253			_aBMJ case reports
260			_c2021
260			_fFY2021
265			_sepublish
266			_d2021-06-07
520			_aSevere anaemia in patients who cannot receive blood transfusion is an indication for the use of hyperbaric oxygen therapy (HBO). Most reports of the use of HBO for anaemia involve patients with acute blood loss. This report details a case of HBO used for a patient with severe pernicious anaemia. A 35-year-old Jehovah's Witnesses believer presented to a hospital with fatigue, dyspnoea and haemoglobin of 26 g/L. She was diagnosed with pernicious anaemia. As she could not receive blood transfusion due to her religious beliefs, vitamin B12 supplementation and HBO were administered and resulted in significant improvement in her condition. The mechanisms of action of HBO, including increased systemic plasma oxygenation, can alleviate signs and symptoms of anaemia regardless of its aetiology. HBO administration can greatly enhance the plasma arterial oxygen content, leading to clinical improvement in patients with anaemia who cannot receive blood transfusion. Copyright (c) BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
656			_aMedStar Institute for Quality and Safety
657			_aJournal Article
700			_aJohnson-Arbor, Kelly
790			_aJohnson-Arbor K, Verstraete R
856			_uhttps://dx.doi.org/10.1136/bcr-2020-240619 _zhttps://dx.doi.org/10.1136/bcr-2020-240619
942			_cART _dArticle
999			_c6342 _d6342