000 03149nam a22004577a 4500
008 211101s20212021 xxu||||| |||| 00| 0 eng d
022 _a0742-2822
040 _aOvid MEDLINE(R)
099 _a34555211
245 _aRight ventricular free wall strain in acutely decompensated heart failure patients with ischemic and non-ischemic cardiomyopathy.
251 _aEchocardiography. 38(10):1747-1753, 2021 10.
252 _aEchocardiography. 38(10):1747-1753, 2021 10.
252 _zEchocardiography. 2021 Sep 23
253 _aEchocardiography (Mount Kisco, N.Y.)
260 _c2021
260 _fFY2022
265 _saheadofprint
265 _sppublish
266 _d2021-11-01
268 _aEchocardiography. 2021 Sep 23
269 _fFY2022
520 _aAIMS: Right ventricular (RV) dysfunction is a predictor of adverse outcomes among patients with HF with reduced ejection fraction (HFrEF); however, differences in RV parameters in HFrEF patients with ischemic (ICM) and non-ischemic cardiomyopathies (NICM) are not well understood. We investigated echocardiographic characteristics, including RV strain, in patients with acute decompensated heart failure (ADHF) and compared patients with ICM and NICM etiology.
520 _aCONCLUSION: Among patients hospitalized with ADHF, patients with nonischemic etiology compared with the patients with ICM, have more severe RV dysfunction measured by RVfwLS, despite similar extent of LV impairment and the same functional limitation class. Copyright (c) 2021 Wiley Periodicals LLC.
520 _aMETHODS: Consecutive patients who presented with ADHF and NYHA class III-IV were prospectively enrolled if they had LVEF < 40% and history of ICM or NICM. All patients underwent clinical exam, laboratory evaluation and 2-D echocardiographic assessment of the left ventricular (LV) and RV function, LV and RV global longitudinal strain (LVGLS, RVGLS), and RV free wall strain (RVfwLS).
520 _aRESULTS: Of 84 patients, 44 had ICM and 40 NICM. The groups had similar blood pressure, NT-proBNP, and echocardiographic parameters of LV function including LVGLS. Absolute RVGLS values were lower than RVfwLS values in both groups. Patients with NICM had significantly lower RVfwLS, but not RVGLS, compared to patients with ICM (-13% to -17%, p = 0.006). Similar differences in RVfwLS were seen in patients in NYHA class III (NICM vs ICM: -13% and -17%, respectively, 95% CI: -8.5 to -.5) and NYHA class IV (NICM vs ICM: -13.8% and -17%, respectively, 95% CI: -6.4 to -.59).
546 _aEnglish
650 _a*Cardiomyopathies
650 _a*Heart Failure
650 _a*Myocardial Ischemia
650 _aHeart Failure/co [Complications]
650 _aHeart Failure/dg [Diagnostic Imaging]
650 _aHumans
650 _aStroke Volume
650 _aVentricular Function, Right
651 _aMedStar Heart & Vascular Institute
657 _aJournal Article
700 _aBarac, Ana
790 _aBakovic D, Barac A, Capkun V, Miric D
856 _uhttps://dx.doi.org/10.1111/echo.15205
_zhttps://dx.doi.org/10.1111/echo.15205
942 _cART
_dArticle
999 _c6742
_d6742