000 03095nam a22003737a 4500
008 220221s20222022 xxu||||| |||| 00| 0 eng d
024 _a10.1093/ofid/ofab591 [doi]
024 _aofab591 [pii]
024 _aPMC8754377 [pmc]
040 _aOvid MEDLINE(R)
099 _a35036460
245 _aDescriptive Epidemiology and Outcomes of Hospitalizations With Complicated Urinary Tract Infections in the United States, 2018.
251 _aOpen Forum Infectious Diseases. 9(1):ofab591, 2022 Jan.
252 _aOpen forum infect. dis.. 9(1):ofab591, 2022 Jan.
253 _aOpen forum infectious diseases
260 _c2022
260 _fFY2022
260 _p2022 Jan
265 _sepublish
266 _d2022-02-21
520 _aBackground: Hospitalizations with complicated urinary tract infection (cUTI) in the United States have increased. Though most often studied as a subset of cUTI, catheter-associated UTI (CAUTI) afflicts a different population of patients and carries outcomes distinct from non-CA cUTI (nCAcUTI). We examined the epidemiology and outcomes of hospitalizations in these groups.
520 _aConclusions: There are >626 000 hospital admissions with a cUTI, comprising ~1.8% of all annual admissions in the United States; 4/5 are nCAcUTI. Because CAUTI is frequently the reason for admission, preventive efforts are needed beyond the acute care setting. Copyright (c) The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
520 _aMethods: We conducted a cross-sectional multicenter study within the 2018 National Inpatient Sample (NIS) database, a 20% stratified sample of discharges from US community hospitals, to explore characteristics and outcomes of patients discharged with a UTI diagnosis. We divided cUTI into mutually exclusive categories of nCAcUTI and CAUTI. We applied survey methods to develop national estimates.
520 _aResults: Among 2 837 385 discharges with a UTI code, 500 400 (17.6%, 19.8% principal diagnosis [PD]) were nCAcUTI and 126 120 (4.4%, 63.8% PD) were CAUTI. Though similar in age (CAUTI, 70.1 years; and nCAcUTI, 69.7 years), patients with nCAcUTI had lower comorbidity (mean Charlson, 4.3) than those with CAUTI (mean Charlson, 4.6). Median (interquartile range [IQR]) length of stay (LOS) was 5 (3-8) days in nCAcUTI and 5 (3-9) days in CAUTI. Overall median (IQR) hospital costs were similar in nCAcUTI (
_9713 [
_5923-
_17 423]) and CAUTI (
_9711 [
_5969-
_17 420]). Though low in both groups, hospital mortality was lower in nCAcUTI (2.8%) than in CAUTI (3.4%). Routine discharges home were higher in nCAcUTI (41.5%) than CAUTI (22.1%).
546 _aEnglish
650 _aIN PROCESS -- NOT YET INDEXED
651 _aMedStar Washington Hospital Center
656 _aMedicine/Pulmonary-Critical Care
657 _aJournal Article
700 _aShorr, Andrew F
790 _aNathanson BH, Shorr AF, Sulham K, Zilberberg MD
856 _uhttps://dx.doi.org/10.1093/ofid/ofab591
_zhttps://dx.doi.org/10.1093/ofid/ofab591
942 _cART
_dArticle
999 _c880
_d880