000 02977nam a22003737a 4500
942 _cART
008 200902s20202020 xxu||||| |||| 00| 0 eng d
040 _aOvid MEDLINE(R)
650 _aIN PROCESS -- NOT YET INDEXED
099 _a32754413
245 _aMonckeberg Medial Calcific Sclerosis of the Temporal Artery Masquerading as Giant Cell Arteritis: Case Reports and Literature Review.
251 _aCureus. 12(7):e9210, 2020 Jul 15.
252 _aCureus. 12(7):e9210, 2020 Jul 15.
190 _aCuevas Castillo FJ
190 _aSujanani S
190 _aChetram VK
190 _aElfishawi M
190 _aAbrudescu A
100 _aChetram, Vishaka K
656 _aMedicine/Internal Medicine
651 _aMedStar Washington Hospital Center
253 _aCureus
520 _aMonckeberg medial calcific sclerosis (MCS) is an infrequent finding in the temporal artery and can clinically present almost indistinguishably from giant cell arteritis (GCA). To our knowledge, there have been only two case reports of suspected GCA found to be MCS only after a temporal artery biopsy (TAB). Herein, we present two cases. The first case is a 69-year-old female with hypertension, type-2 diabetes mellitus, and chronic headaches who presented with left temporal headaches and scalp tenderness. She had a prominently dilated, tortuous, and tender left temporal artery. Initial labs showed a leukocyte count of 11.1x103/L, erythrocyte sedimentation rate (ESR) of 29 mm/hr, and C-reactive protein (CRP) of 5.8 mg/L. The patient was started on prednisone 60 mg for presumptive GCA. Left TAB was negative for inflammatory changes, with findings consistent with MCS. Steroids were discontinued, and symptoms resolved. The second case is a 67-year-old male with hypertension, asthma, hyperlipidemia, status-post left eye cataract phacoemulsification, with intraocular lens insertion one-month prior, who presented with left eye blurriness in the inferior visual field and intermittent headache for 15 days. Left ophthalmoscopy showed retinal pallor and edema. Initial labs revealed ESR of 25 mm/hr, CRP of 11.2 mg/L, leukocyte count of 13.01x103/L. The patient was given solumedrol 120 mg once and prednisone 70 mg daily for presumptive GCA. Left TAB was negative for GCA but reported damaged elastic fibers by calcification consistent with MCS. Partial visual blurriness remained, and steroids were discontinued. This report accentuates the importance of MCS as a temporal GCA simulator. Physicians should be aware that TAB potentially changes management and may help surface underlying conditions. Copyright (c) 2020, Cuevas Castillo et al.
022 _a2168-8184
857 _uhttps://dx.doi.org/10.7759/cureus.9210
856 _uhttps://dx.doi.org/10.7759/cureus.9210
657 _aCase Reports
024 _a10.7759/cureus.9210 [doi]
024 _aPMC7387070 [pmc]
260 _sepublish
546 _aEnglish
260 _c2020
269 _fFY2021
999 _c8970
_d8970