My Bleeding Nephrons!.
My Bleeding Nephrons!.
- 2019
Anticoagulation-related nephropathy (ARN) is an uncommon diagnosis that should be considered in patients presenting with unexplained acute kidney injury (AKI) and coagulopathy. In this article, we present the case of a 70-year-old male with a history of cirrhosis and portal vein thrombosis on Coumadin who presented to the hospital with gross hematuria. The patient was diagnosed with AKI on chronic kidney disease (CKD) secondary to ARN superimposed on sclerosing IgA nephropathy. ARN, also known as warfarin-associated nephropathy, is an uncommon condition in which AKI from glomerular hemorrhage develops in a patient with an international normalized ratio greater than 3. The most common risk factor for development of ARN is CKD. AKI in our patient unearthed preexisting CKD due to IgA nephropathy as evidenced by the biopsy.
English
2324-7096
10.1177/2324709619858126 [doi] PMC6587381 [pmc]
*Acute Kidney Injury/et [Etiology]
*Anticoagulants/ae [Adverse Effects]
*Glomerulonephritis, IGA/co [Complications]
*Kidney Glomerulus/pa [Pathology]
*Warfarin/ae [Adverse Effects]
Acute Kidney Injury/pa [Pathology]
Aged
Glomerulonephritis, IGA/di [Diagnosis]
Glomerulonephritis, IGA/pa [Pathology]
Hematuria/et [Etiology]
Humans
International Normalized Ratio
Kidney Glomerulus/de [Drug Effects]
Kidney/bs [Blood Supply]
Male
Renal Insufficiency, Chronic/ci [Chemically Induced]
Renal Insufficiency, Chronic/pp [Physiopathology]
Risk Factors
MedStar Washington Hospital Center
Medicine/Internal Medicine
Journal Article
Anticoagulation-related nephropathy (ARN) is an uncommon diagnosis that should be considered in patients presenting with unexplained acute kidney injury (AKI) and coagulopathy. In this article, we present the case of a 70-year-old male with a history of cirrhosis and portal vein thrombosis on Coumadin who presented to the hospital with gross hematuria. The patient was diagnosed with AKI on chronic kidney disease (CKD) secondary to ARN superimposed on sclerosing IgA nephropathy. ARN, also known as warfarin-associated nephropathy, is an uncommon condition in which AKI from glomerular hemorrhage develops in a patient with an international normalized ratio greater than 3. The most common risk factor for development of ARN is CKD. AKI in our patient unearthed preexisting CKD due to IgA nephropathy as evidenced by the biopsy.
English
2324-7096
10.1177/2324709619858126 [doi] PMC6587381 [pmc]
*Acute Kidney Injury/et [Etiology]
*Anticoagulants/ae [Adverse Effects]
*Glomerulonephritis, IGA/co [Complications]
*Kidney Glomerulus/pa [Pathology]
*Warfarin/ae [Adverse Effects]
Acute Kidney Injury/pa [Pathology]
Aged
Glomerulonephritis, IGA/di [Diagnosis]
Glomerulonephritis, IGA/pa [Pathology]
Hematuria/et [Etiology]
Humans
International Normalized Ratio
Kidney Glomerulus/de [Drug Effects]
Kidney/bs [Blood Supply]
Male
Renal Insufficiency, Chronic/ci [Chemically Induced]
Renal Insufficiency, Chronic/pp [Physiopathology]
Risk Factors
MedStar Washington Hospital Center
Medicine/Internal Medicine
Journal Article