MARC details
| 000 -LEADER |
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| fixed length control field |
03307nam a22003617a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
170428s20172017 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1083-3188 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
28216128 |
| 245 ## - TITLE STATEMENT |
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| Title |
Mucinous Cystadenoma in Children and Adolescents. |
| 251 ## - Source |
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| Source |
Journal of Pediatric & Adolescent Gynecology. 30(4):495-498, 2017 Aug |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J Pediatr Adolesc Gynecol. 30(4):495-498, 2017 Aug |
| 253 ## - Journal Name |
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| Journal name |
Journal of pediatric and adolescent gynecology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2017 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2017 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2017-05-06 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online through MWHC library: 2002 - presentMH - AdolescentMH - ChildMH - *Chromogranins/ge [Genetics]MH - Cystadenoma, Mucinous/ge [Genetics]MH - *Cystadenoma, Mucinous/pa [Pathology]MH - Cystadenoma, Mucinous/th [Therapy]MH - Databases, FactualMH - FemaleMH - *GTP-Binding Protein alpha Subunits, Gs/ge [Genetics]MH - HumansMH - MutationMH - Neoplasm Recurrence, Local/su [Surgery]MH - Ovarian Neoplasms/su [Surgery]MH - Ovariectomy |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: This series supports the use of ovary-sparing surgery in the treatment of MCA. Further research exploring possible genetic variants such as the GNAS gene in children and adolescents diagnosed with MCA is warranted. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Copyright (c) 2017. Published by Elsevier Inc. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
DESIGN: and Participants: After Institutional Board Review approval, the pathology database of a large urban children's hospital was queried to identify adolescents with MCA between the years 2008 and 2014. 14 patients, aged 8-18 years (median 14), were identified. A buccal swab for genetic testing was obtained from a subset of consenting patients. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
MAIN OUTCOME MEASURES: MCA recurrence; ovarian return to normal size; GNAS gene variants. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: Two patients underwent oophorectomies, while the remaining 12 underwent cystectomies. Follow-up ultrasound revealed slow return of ovary to normal size. Of the 10 patients with available follow-up data, there were no recurrences at a median of 225 days from surgery. Four patients consented to a buccal swab for genetic testing, and the GNAS gene was noted to have rare variants in 2 patients. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
STUDY OBJECTIVE: Mucinous cystadenomas (MCAs) are benign epithelial ovarian tumors that occur rarely in children and adolescents. As children and adolescents typically have their childbearing years ahead of them, conservative therapy is indicated. However, there is concern that ovarian cystectomy may be associated with significant recurrence risk in MCA. Furthermore, GNAS gene mutations are associated with McCune-Albright Syndrome, which is associated with cystic ovaries. We sought to evaluate the outcomes of children and adolescents with MCA treated conservatively. A subset of patients underwent GNAS gene testing. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Obstetrics and Gynecology/Pediatric and Adolescent |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Cowan, Renee A |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Gomez-Lobo, Veronica |
| 790 ## - Authors |
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| All authors |
Cowan RA, Faucz FR, Gomez-Lobo V, Haber EN, Stratakis CA |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.jpag.2017.02.001">https://dx.doi.org/10.1016/j.jpag.2017.02.001</a> |
| Public note |
https://dx.doi.org/10.1016/j.jpag.2017.02.001 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
