MARC details
000 -LEADER |
fixed length control field |
02834nam a22003617a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
190128s20192019 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0269-9370 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1097/QAD.0000000000002151 [doi] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
30664005 |
245 ## - TITLE STATEMENT |
Title |
Associations between lipids and subclinical coronary atherosclerosis. |
251 ## - Source |
Source |
AIDS. 2019 Jan 16 |
252 ## - Abbreviated Source |
Abbreviated source |
AIDS. 2019 Jan 16 |
253 ## - Journal Name |
Journal name |
AIDS (London, England) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2019 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2019 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2019-01-28 |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSION: The associations between lipids and coronary atherosclerosis tended to be weaker for HIV+ compared to HIV- men, although TC/HDL had the strongest association for both HIV+ and HIV- men. A weaker association between lipid levels and coronary atherosclerosis for HIV+ men may contribute to the decreased discrimination of CVD risk observed in HIV+ individuals. |
520 ## - SUMMARY, ETC. |
Abstract |
DESIGN: The Multicenter AIDS Cohort Study (MACS) is an observational cohort with a total of 429 HIV+ and 303 HIV- men who had non-contrast cardiac computed tomography (CT) performed to measure coronary artery calcium (CAC) and coronary CT angiography to measure coronary stenosis, coronary plaque presence, and composition. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: We used multivariable adjusted prevalence ratios (PR) to examine the relationship between the standard deviation (SD) difference in each lipid parameter and coronary atherosclerosis. |
520 ## - SUMMARY, ETC. |
Abstract |
OBJECTIVE: Whether HIV modifies the relationship of serum lipids with coronary atherosclerosis and coronary plaque subtypes is uncertain. We examined the associations between traditional lipids and coronary atherosclerosis among HIV-infected (HIV+) and HIV-uninfected (HIV-) men. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Total cholesterol (TC) / HDL-C had the strongest associations with coronary atherosclerosis regardless of HIV status. Overall, lipid parameters were most strongly associated with the presence of mixed plaque, stenosis >50%, and CAC for both HIV+ and HIV- men. HIV+ men had similar, but weaker associations, between lipid parameters and coronary atherosclerosis compared to HIV- men. The strongest association was between the TC/HDL-C and stenosis >50% for both HIV+ [PR 1.25 per SD (95% CI 1.07-1.43)] and HIV- men [PR 1.46 per SD (95% CI 1.08-1.85)]. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Union Memorial Hospital |
656 ## - INDEX TERM--OCCUPATION |
Department |
Cardiology |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Zikusoka, Michelle |
790 ## - Authors |
All authors |
Brown TT, Budoff M, Deal JA, Jacobson LP, Kingsley L, Palella FJ Jr, Post WS, Sarkar S, Whelton SP, Witt MD, Zikusoka M |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1097/QAD.0000000000002151">https://dx.doi.org/10.1097/QAD.0000000000002151</a> |
Public note |
https://dx.doi.org/10.1097/QAD.0000000000002151 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |