Ultrasound-guided foam sclerotherapy as a therapeutic modality in venous ulceration. [Review]

MedStar author(s):
Citation: Surgeon Journal of the Royal Colleges of Surgeons of Edinburgh & Ireland. 20(5):e206-e213, 2022 Oct.PMID: 34629303Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal Article | Meta-Analysis | Review | Systematic ReviewSubject headings: *Varicose Ulcer | *Varicose Veins | Humans | Prospective Studies | Recurrence | Saphenous Vein | Sclerotherapy/ae [Adverse Effects] | Sclerotherapy/mt [Methods] | Treatment Outcome | Ulcer/et [Etiology] | Ultrasonography, Interventional | Varicose Ulcer/dg [Diagnostic Imaging] | Varicose Ulcer/et [Etiology] | Varicose Ulcer/th [Therapy] | Varicose Veins/et [Etiology]Year: 2022ISSN:
  • 1479-666X
Name of journal: The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and IrelandAbstract: CONCLUSION: A prospective, trial is warranted in order to determine the true merits of UGFS in the setting of venous ulceration. Copyright © 2021 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.METHODS: The MEDLINE, CENTRAL and Embase databases were used to search for relevant studies using the terms ' (sclerotherapy AND ulcer) OR (vein AND ulcer) OR (sclerotherapy AND vein)'. Heterogeneity between studies was quantified using the I2 statistic. A random effects model was used to calculate risk ratios where substantial heterogeneity was found.OBJECTIVES: The objective of this systematic review and meta-analysis was to evaluate rates of ulcer healing following ultrasound-guided foam sclerotherapy (UGFS).RESULTS: The initial search yielded 8266 articles. 8 studies were included in the qualitative synthesis and 3 in the meta-analysis. Superior complete ulcer healing rates were noted in patients treated with foam sclerotherapy versus compression therapy alone (pooled OR 6.41, 95% CI = 0.3-148.2, p = 0.246, random effects method). A marked degree of heterogeneity was observed between studies (I2 = 81%).All authors: De Freitas S, Joyce DP, Tang TY, Tubassam M, Walsh SR, Woo EYFiscal year: FY2023Digital Object Identifier: Date added to catalog: 2022-10-20
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Journal Article MedStar Authors Catalog Article 34629303 Available 34629303

CONCLUSION: A prospective, trial is warranted in order to determine the true merits of UGFS in the setting of venous ulceration. Copyright © 2021 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

METHODS: The MEDLINE, CENTRAL and Embase databases were used to search for relevant studies using the terms ' (sclerotherapy AND ulcer) OR (vein AND ulcer) OR (sclerotherapy AND vein)'. Heterogeneity between studies was quantified using the I2 statistic. A random effects model was used to calculate risk ratios where substantial heterogeneity was found.

OBJECTIVES: The objective of this systematic review and meta-analysis was to evaluate rates of ulcer healing following ultrasound-guided foam sclerotherapy (UGFS).

RESULTS: The initial search yielded 8266 articles. 8 studies were included in the qualitative synthesis and 3 in the meta-analysis. Superior complete ulcer healing rates were noted in patients treated with foam sclerotherapy versus compression therapy alone (pooled OR 6.41, 95% CI = 0.3-148.2, p = 0.246, random effects method). A marked degree of heterogeneity was observed between studies (I2 = 81%).

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