The Effect of Maternal Obesity on Oxytocin Requirements to Achieve Vaginal Delivery.
Citation: American Journal of Perinatology. 37(4):349-356, 2020 03.PMID: 31430825Institution: MedStar Washington Hospital CenterDepartment: Obstetrics and Gynecology/Maternal-Fetal MedicineForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Labor, Induced | *Obesity, Maternal | *Oxytocics/ad [Administration & Dosage] | *Oxytocin/ad [Administration & Dosage] | Adolescent | Adult | Body Mass Index | Delivery, Obstetric | Dose-Response Relationship, Drug | Female | Humans | Middle Aged | Overweight | Pregnancy | Retrospective Studies | Young AdultYear: 2020ISSN:- 0735-1631
- Adams, April D:
- https://orcid.org/0000-0001-7776-2941
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 31430825 | Available | 31430825 |
CONCLUSION: Obese women are more likely to require oxytocin rates more than 20 mU/min, higher doses of oxytocin, and greater duration of oxytocin exposure to achieve a vaginal delivery.
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OBJECTIVE: Our objective was to determine if obese women are more likely to require oxytocin rates > 20 mU/min to achieve vaginal delivery, compared with normal weight women.
RESULTS: There were 4,284 births included in the analysis. Thirty-three per cent of deliveries were among women classified as overweight (body mass index [BMI] 25-29.9 kg/m<sup>2</sup>) and 58% were among women classified as obese (BMI >30.0 kg/m<sup>2</sup>), 12% were classified as class III obesity (BMI >40 kg/m<sup>2</sup>). Overall 110 (2.6%) women required an oxytocin rate of >20 mU/min. Doses of oxytocin >20 mU/min for women in the overweight, class I obesity, and class II obesity groups were 2.6, 1.9, and 1.6%, respectively. Deliveries among women with class III obesity had a significantly longer duration of oxytocin exposure (10.7 hours) compared with the normal weight group (8.2 hours, p < 0.001), and had a higher maximum rate of oxytocin compared (10 mU/min) to normal weight women (8 mU/min, p < 0.001).
STUDY DESIGN: This is a retrospective cohort study of deliveries at the MedStar Washington Hospital Center and MedStar Georgetown University Hospital.
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