Silent and formidable foe: neuroendocrine tumours of the gallbladder.
Silent and formidable foe: neuroendocrine tumours of the gallbladder.
- 2020
Neuroendocrine neoplasms of the gallbladder occur infrequently, with the diagnosis being incidental in most cases. We present a case of an 81-year-old African American woman who initially presented with acute suppurative cholecystitis, found on pathology to have a moderately differentiated infiltrating adenocarcinoma. A partial hepatic resection with periportal lymph node dissection was planned which was subsequently aborted intraoperatively due to the presence of diffuse carcinomatosis. Pathology of the cancerous lesions revealed neuroendocrine carcinoma. Gallbladder neuroendocrine tumours demonstrate no specific clinical features. Given its often late presentation, neuroendocrine tumours of the gallbladder pose a therapeutic and prognostic challenge. Copyright (c) BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.
English
1757-790X
10.1136/bcr-2020-237063 [doi] 13/12/e237063 [pii] PMC7757469 [pmc]
*Carcinoma, Neuroendocrine/di [Diagnosis]
*Cholecystitis, Acute/et [Etiology]
*Gallbladder Neoplasms/di [Diagnosis]
*Gallbladder/pa [Pathology]
*Peritoneal Neoplasms/di [Diagnosis]
Aged, 80 and over
Carcinoma, Neuroendocrine/sc [Secondary]
Carcinoma, Neuroendocrine/th [Therapy]
Cholecystectomy, Laparoscopic
Cholecystitis, Acute/su [Surgery]
Fatal Outcome
Female
Gallbladder Neoplasms/co [Complications]
Gallbladder Neoplasms/pa [Pathology]
Gallbladder Neoplasms/th [Therapy]
Gallbladder/dg [Diagnostic Imaging]
Gallbladder/su [Surgery]
Hospice Care
Humans
Missed Diagnosis
Neoplasm Staging
Peritoneal Neoplasms/sc [Secondary]
Peritoneal Neoplasms/th [Therapy]
Tomography, X-Ray Computed
MedStar Medical Group
MedStar Health Baltimore Residents
Journal Article
Neuroendocrine neoplasms of the gallbladder occur infrequently, with the diagnosis being incidental in most cases. We present a case of an 81-year-old African American woman who initially presented with acute suppurative cholecystitis, found on pathology to have a moderately differentiated infiltrating adenocarcinoma. A partial hepatic resection with periportal lymph node dissection was planned which was subsequently aborted intraoperatively due to the presence of diffuse carcinomatosis. Pathology of the cancerous lesions revealed neuroendocrine carcinoma. Gallbladder neuroendocrine tumours demonstrate no specific clinical features. Given its often late presentation, neuroendocrine tumours of the gallbladder pose a therapeutic and prognostic challenge. Copyright (c) BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.
English
1757-790X
10.1136/bcr-2020-237063 [doi] 13/12/e237063 [pii] PMC7757469 [pmc]
*Carcinoma, Neuroendocrine/di [Diagnosis]
*Cholecystitis, Acute/et [Etiology]
*Gallbladder Neoplasms/di [Diagnosis]
*Gallbladder/pa [Pathology]
*Peritoneal Neoplasms/di [Diagnosis]
Aged, 80 and over
Carcinoma, Neuroendocrine/sc [Secondary]
Carcinoma, Neuroendocrine/th [Therapy]
Cholecystectomy, Laparoscopic
Cholecystitis, Acute/su [Surgery]
Fatal Outcome
Female
Gallbladder Neoplasms/co [Complications]
Gallbladder Neoplasms/pa [Pathology]
Gallbladder Neoplasms/th [Therapy]
Gallbladder/dg [Diagnostic Imaging]
Gallbladder/su [Surgery]
Hospice Care
Humans
Missed Diagnosis
Neoplasm Staging
Peritoneal Neoplasms/sc [Secondary]
Peritoneal Neoplasms/th [Therapy]
Tomography, X-Ray Computed
MedStar Medical Group
MedStar Health Baltimore Residents
Journal Article