Early Ventricular Arrhythmias after Left Ventricular Assist Device Implantation.
Early Ventricular Arrhythmias after Left Ventricular Assist Device Implantation.
- 2023
BACKGROUND: While sustained ventricular arrhythmias are a common complication following durable left ventricular assist device (LVAD) implantation, the incidence, risk factors, and prognostic implications of early postoperative ventricular arrhythmias (EVAs) in contemporary LVAD patients are poorly understood. CONCLUSION: EVAs are common after durable LVAD implantation and are associated with increased risk of 30-day mortality. Copyright © 2023. Published by Elsevier Inc. METHODS: A single-center retrospective analysis was performed of patients who underwent LVAD implantation from 10/1/2006-10/1/2022. EVA was defined as an episode of sustained ventricular arrhythmia identified <=30 days after LVAD implantation. RESULTS: A total of 789 patients underwent LVAD implantation (age: mean 62.9 years +/- 0.5, HeartMate 3: 41.4%, destination therapy: 43.3%). EVAs occurred in 100 (12.7%) patients. A history of ESRD (OR 5.6, CI 1.45-21.70), preoperative electrical storm (OR 2.82, CI 1.11-7.16) and appropriate ICD therapy prior to implantation (OR 2.8, CI 1.26-6.19) are independently associated with EVAs. EVA was associated with decreased 30-day survival (HR 3.02; 1.1-8.3 95% CI; p=0.032). There was no difference in transplant-free survival time between patients with and without EVAs (HR 0.82; 0.5-1.4 95% CI; p=0.454).
English
1071-9164
10.1016/j.cardfail.2023.11.018 [doi] S1071-9164(23)00912-0 [pii]
IN PROCESS -- NOT YET INDEXED
MedStar Heart & Vascular Institute
MedStar Washington Hospital Center
Cardiovascular Disease Fellowship
Clinical Cardiac Electrophysiology Fellowship
Internal Medicine Residency
MedStar Georgetown University Hospital/MedStar Washington Hospital Center
Surgery/Surgical Critical Care
Journal Article
BACKGROUND: While sustained ventricular arrhythmias are a common complication following durable left ventricular assist device (LVAD) implantation, the incidence, risk factors, and prognostic implications of early postoperative ventricular arrhythmias (EVAs) in contemporary LVAD patients are poorly understood. CONCLUSION: EVAs are common after durable LVAD implantation and are associated with increased risk of 30-day mortality. Copyright © 2023. Published by Elsevier Inc. METHODS: A single-center retrospective analysis was performed of patients who underwent LVAD implantation from 10/1/2006-10/1/2022. EVA was defined as an episode of sustained ventricular arrhythmia identified <=30 days after LVAD implantation. RESULTS: A total of 789 patients underwent LVAD implantation (age: mean 62.9 years +/- 0.5, HeartMate 3: 41.4%, destination therapy: 43.3%). EVAs occurred in 100 (12.7%) patients. A history of ESRD (OR 5.6, CI 1.45-21.70), preoperative electrical storm (OR 2.82, CI 1.11-7.16) and appropriate ICD therapy prior to implantation (OR 2.8, CI 1.26-6.19) are independently associated with EVAs. EVA was associated with decreased 30-day survival (HR 3.02; 1.1-8.3 95% CI; p=0.032). There was no difference in transplant-free survival time between patients with and without EVAs (HR 0.82; 0.5-1.4 95% CI; p=0.454).
English
1071-9164
10.1016/j.cardfail.2023.11.018 [doi] S1071-9164(23)00912-0 [pii]
IN PROCESS -- NOT YET INDEXED
MedStar Heart & Vascular Institute
MedStar Washington Hospital Center
Cardiovascular Disease Fellowship
Clinical Cardiac Electrophysiology Fellowship
Internal Medicine Residency
MedStar Georgetown University Hospital/MedStar Washington Hospital Center
Surgery/Surgical Critical Care
Journal Article