Predictors of 130912 in pain and physical functioning among post-menopausal women with recurrent pain conditions in the women's health initiative observational cohort.

Predictors of 130912 in pain and physical functioning among post-menopausal women with recurrent pain conditions in the women's health initiative observational cohort. - 2012

Available online from MWHC library: 2000 - 2008

Pain complaints are commonly reported symptoms among postmenopausal women and can have significant effects on health-related quality of life. We sought to identify medical and psychosocial factors that predict 130912s in pain and overall physical functioning over a 3-year period among postmenopausal women with recurrent pain conditions. We examined data from postmenopausal women age 50 to 79 with recurrent pain conditions (low back pain, neck pain, headache or migraines, or joint pain or stiffness) over a 3-year period using the Women's Health Initiative Observational Study Cohort (N = 67,963). Multinomial logistic regression models controlling for demographic and clinical characteristics were used to identify baseline predictors of 130912 in the SF-36 subscales for pain and physical functioning between baseline and 3-year follow-up. Body mass index (BMI) was associated with worsening of pain (OR [95% CI] 1.54 [1.45-1.63] for BMI >=30) and physical functioning (1.83 [1.71-1.95] for BMI >=30). A higher reported number of nonpain symptoms, higher medical comorbidity, and a positive screen for depression (1.13 [1.05-1.22] for worsened pain) were also associated with worsening of pain and physical functioning. Baseline prescription opioid use was also associated with lack of improvement in pain (OR .42, 95% CI .36-.49) and with worsened physical functioning (1.25 [1.04-1.51]). PERSPECTIVE: This study presents prospective data on 130912 in pain and physical functioning in postmenopausal women over a 3-year period. Our results suggest depression, nonpain physical symptoms, obesity, and possibly opioid treatment are associated with worse long-term pain outcomes in this population. Copyright 2012 American Pain Society. Published by Elsevier Inc. All rights reserved.


English

1526-5900


*Health Status
*Motor Activity/ph [Physiology]
*Pain/ep [Epidemiology]
*Pain/pp [Physiopathology]
*Women's Health
Aged
Body Mass Index
Cohort Studies
Depression
Female
Humans
Logistic Models
Longitudinal Studies
Middle Aged
Observation
Pain/dt [Drug Therapy]
Pain/px [Psychology]
Postmenopause
Predictive Value of Tests
Quality of Life
Randomized Controlled Trials as Topic


MedStar Washington Hospital Center


Medicine/Rheumatology


Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

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