Atypical Schwannoma: A 10-year experience.
Atypical Schwannoma: A 10-year experience.
- 2020
CONCLUSIONS: Atypical schwannoma is an intermediate disease process with an accelerated clinical course and higher recurrence rate as compared to vestibular schwannoma. Traditional operative approaches may be employed without increased concern for post-operative complications. Thorough counseling and close follow-up should be offered to these patients given the higher recurrence rate. Larger studies are required to determine if these patients need more frequent MRIs for long-term surveillance. Copyright (c) 2019 Elsevier Inc. All rights reserved. MAIN OUTCOMES MEASURE: Demographic data of the cohort were recorded. Findings on pathology were evaluated. Initial treatment and post-operative course was recorded. Main outcome measures were clinical presentation, including cranial nerve deficits at the time of presentation, complication and recurrence rates. MATERIALS AND METHODS: The study design was retrospective case review of patients with the histopathologic diagnosis of atypical and benign schwannoma of the cerebellopontine angle diagnosed at the study institution over a 10-year period. OBJECTIVE: The goal of this study was to describe the clinical presentation associated with atypical schwannoma of the cerebellopontine angle, characterize the pathologic findings and describe the long-term outcome. RESULTS: At presentation, a somewhat accelerated course of cranial nerve deficit was noted among patients with atypical schwannoma as compared to benign schwannoma. In the immediate post-operative period, there were no differences noted in the complication rate. Atypical schwannomas appear to have higher recurrence rate compared to benign schwannomas. SETTING: Tertiary referral center.
English
0196-0709
10.1016/j.amjoto.2019.102309 [doi] S0196-0709(19)30906-8 [pii]
*Cerebellar Neoplasms/pa [Pathology]
*Cerebellopontine Angle/pa [Pathology]
*Neurilemmoma/pa [Pathology]
Cerebellar Neoplasms/su [Surgery]
Cerebellopontine Angle/su [Surgery]
Female
Humans
Male
Middle Aged
Neoplasm Recurrence, Local
Neurilemmoma/su [Surgery]
Retrospective Studies
MedStar Washington Hospital Center
Otolaryngology
Journal Article
CONCLUSIONS: Atypical schwannoma is an intermediate disease process with an accelerated clinical course and higher recurrence rate as compared to vestibular schwannoma. Traditional operative approaches may be employed without increased concern for post-operative complications. Thorough counseling and close follow-up should be offered to these patients given the higher recurrence rate. Larger studies are required to determine if these patients need more frequent MRIs for long-term surveillance. Copyright (c) 2019 Elsevier Inc. All rights reserved. MAIN OUTCOMES MEASURE: Demographic data of the cohort were recorded. Findings on pathology were evaluated. Initial treatment and post-operative course was recorded. Main outcome measures were clinical presentation, including cranial nerve deficits at the time of presentation, complication and recurrence rates. MATERIALS AND METHODS: The study design was retrospective case review of patients with the histopathologic diagnosis of atypical and benign schwannoma of the cerebellopontine angle diagnosed at the study institution over a 10-year period. OBJECTIVE: The goal of this study was to describe the clinical presentation associated with atypical schwannoma of the cerebellopontine angle, characterize the pathologic findings and describe the long-term outcome. RESULTS: At presentation, a somewhat accelerated course of cranial nerve deficit was noted among patients with atypical schwannoma as compared to benign schwannoma. In the immediate post-operative period, there were no differences noted in the complication rate. Atypical schwannomas appear to have higher recurrence rate compared to benign schwannomas. SETTING: Tertiary referral center.
English
0196-0709
10.1016/j.amjoto.2019.102309 [doi] S0196-0709(19)30906-8 [pii]
*Cerebellar Neoplasms/pa [Pathology]
*Cerebellopontine Angle/pa [Pathology]
*Neurilemmoma/pa [Pathology]
Cerebellar Neoplasms/su [Surgery]
Cerebellopontine Angle/su [Surgery]
Female
Humans
Male
Middle Aged
Neoplasm Recurrence, Local
Neurilemmoma/su [Surgery]
Retrospective Studies
MedStar Washington Hospital Center
Otolaryngology
Journal Article